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Article
Open AccessSmall noncoding RNAs and sperm nuclear basic proteins reflect the environmental impact on germ cells
Molecular techniques can complement conventional spermiogram analyses to provide new information on the fertilizing potential of spermatozoa and to identify early alterations due to environmental pollution.
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Article
Open AccessProfiling small RNAs in fecal immunochemical tests: is it possible?
Fecal microRNAs represent promising molecules with potential clinical interest as non-invasive diagnostic and prognostic biomarkers. Colorectal cancer (CRC) screening based on the fecal immunochemical test (FI...
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Article
Apremilast retention rate in clinical practice: observations from an Italian multi-center study
There are few real-world setting studies focused on apremilast effectiveness (i.e., retention rate) in psoriatic arthritis (PsA). The main aim of this retrospective observational study is the assessment of apr...
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Article
Open AccessIntegrative genomic and transcriptomic analyses illuminate the ontology of HER2-low breast carcinomas
The “HER2-low” nomenclature identifies breast carcinomas (BCs) displaying a HER2 score of 1+/2+ in immunohistochemistry and lacking ERBB2 amplification. Whether HER2-low BCs (HLBCs) constitute a distinct entity i...
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Article
Open AccessCombined miRNA and SERS urine liquid biopsy for the point-of-care diagnosis and molecular stratification of bladder cancer
Bladder cancer (BC) has the highest per-patient cost of all cancer types. Hence, we aim to develop a non-invasive, point-of-care tool for the diagnostic and molecular stratification of patients with BC based o...
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Article
Open AccessFaecal miRNA profiles associated with age, sex, BMI, and lifestyle habits in healthy individuals
For their stability and detectability faecal microRNAs represent promising molecules with potential clinical interest as non-invasive diagnostic and prognostic biomarkers. However, there is no evidence on how ...
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Protocol
Computational Analysis of circRNA Expression Data
Analysis of circular RNA (circRNA) expression from RNA-Seq data can be performed with different algorithms and analysis pipelines, tools allowing the extraction of heterogeneous information on the expression o...
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Article
Author Correction: Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Metagenomic analysis of colorectal cancer datasets identifies cross-cohort microbial diagnostic signatures and a link with choline degradation
Several studies have investigated links between the gut microbiome and colorectal cancer (CRC), but questions remain about the replicability of biomarkers across cohorts and populations. We performed a meta-an...
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Article
Open AccessReproducible bioinformatics project: a community for reproducible bioinformatics analysis pipelines
Reproducibility of a research is a key element in the modern science and it is mandatory for any industrial application. It represents the ability of replicating an experiment independently by the location and...
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Article
Effect of intra-articular injection of intermediate-weight hyaluronic acid on hip and knee cartilage: in-vivo evaluation using T2 map**
We used T2 map** to quantify the effect of intra-articular hyaluronic acid administration (IAHAA) on cartilage with correlation to clinical symptoms.
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Article
Open AccessDissecting the genomic activity of a transcriptional regulator by the integrative analysis of omics data
In the study of genomic regulation, strategies to integrate the data produced by Next Generation Sequencing (NGS)-based technologies in a meaningful ensemble are eagerly awaited and must continuously evolve. H...
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Article
Ultrasound-guided percutaneous injection to treat de Quervain’s disease using three different techniques: a randomized controlled trial
To compare the six-month outcome of three different ultrasound-guided treatments for de Quervain’s disease (DQD).
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Chapter
Flexor Muscles
Ultrasound images are coupled with anatomical schemes explaining the probe positioning and scanning technique for the various muscles of the thigh and leg. For each muscle, a brief explanation of normal anatom...
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Chapter
Drainage of Articular Ganglia Around the Ankle
Ganglion cysts are the most common benign soft-tissue lesions of the ankle. They predominantly occur in young adults. In 60–70 % of cases, the ganglion cyst originates from the subtalar joint and communicates ...
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Chapter
The Hip: Focused Ultrasound Anatomy and Examination Technique
The hip can be divided into four compartments: anterior, medial, lateral and posterior.
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Chapter
Hip Insertional Tendinopathy
Tendons around the hip can develop degenerative changes at the site of insertion as a result of chronic microtraumatism due to overload or previous poorly healed acute injuries. Accurate anamnestic data collec...
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Chapter
Quadriceps
Ultrasound images are coupled with anatomical schemes explaining the probe positioning and scanning technique for the quadriceps muscles. For each muscle, a brief explanation of normal anatomy is also provided...
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Chapter
Hip Intra-articular Injections
Intra-articular injections of the hip can be performed to treat a number of pathologic conditions. The drugs administered in these cases may be anti-inflammatory agents, such as steroids that may be indicated ...
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Chapter
The Wrist: Focused US Anatomy and Examination Technique
On the dorsal side of the wrist, the extensor tendons run within six compartments, numbered from 1 to 6, from the radial to the ulnar side. The first compartment consists of the abductor pollicis longus and ex...
