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Article
Open AccessSelective expansion of myeloid and NK cells in humanized mice yields human-like vaccine responses
Mice engrafted with components of a human immune system have become widely-used models for studying aspects of human immunity and disease. However, a defined methodology to objectively measure and compare the ...
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Article
Open AccessSingle-cell tracking of flavivirus RNA uncovers species-specific interactions with the immune system dictating disease outcome
Positive-sense RNA viruses pose increasing health and economic concerns worldwide. Our limited understanding of how these viruses interact with their host and how these processes lead to virulence and disease ...
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Protocol
Generation of Human Liver Chimeric Mice for the Study of Human Hepatotropic Pathogens
Human liver chimeric mice have become valuable tools for the study of human hepatotropic pathogens and for the investigation of metabolism and pharmacokinetics of novel drugs. The evolution of the underlying m...
