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Article
Long-term results of the Italian Association of Pediatric Hematology and Oncology (AIEOP) Studies 82, 87, 88, 91 and 95 for childhood acute lymphoblastic leukemia
We analyzed the long-term outcome of 4865 patients treated in Studies 82, 87, 88, 91 and 95 for childhood acute lymphoblastic leukemia (ALL) of the Italian Association of Pediatric Hematology and Oncology (AIE...
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Article
DNA copy-number abnormalities do not occur in infant ALL with t(4;11)/MLL-AF4
The pathogenesis of infant acute lymphoblastic leukemia (ALL) is still not well defined. Short latency to leukemia and very high concordance rate for ALL in Mixed-Lineage Leukemia (MLL)-positive infant twins sugg...
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Article
The MIF-173G/C polymorphism does not contribute to prednisone poor response in vivo in childhood acute lymphoblastic leukemia
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Article
CD1d expression on B-precursor acute lymphoblastic leukemia subsets with poor prognosis
Acute lymphoblastic leukemia (ALL) is the most frequent malignancy of childhood. Although therapeutical advances have been achieved, some ALL subgroups still fare poorly. CD1d is a monomorphic molecule that pr...
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Article
Genetic polymorphism of NAD(P)H:quinone oxidoreductase is associated with an increased risk of infant acute lymphoblastic leukemia without MLL gene rearrangements
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a detoxification enzyme that protects cells against oxidative stress and toxic quinones. A polymorphism (C609T) in the gene produces in the heterozygous individuals (...
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Article
Pre-transplant prognostic factors for patients with high-risk leukemia undergoing an unrelated cord blood transplantation
From July 1995 to December 2001, 42 patients with leukemia aged 1–42 years underwent cord blood transplant (CBT) from unrelated, ⩽2 antigen HLA mismatched donors. In all, 26 patients were in ⩽2nd complete remi...
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Article
Reciprocal bone marrow transplantation between brother and sister
A child with AML underwent allogeneic BMT from an HLA-identical sister donor. Prompt and stable trilineage engraftment occurred and after few months he returned to a normal life. Eight years later a primary NH...
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Article
SPET monitoring of auditory cortex activation by electric stimulation in a patient with auditory brainstem implant
Auditory cortex activation following multifrequency acoustic stimulation has been evaluated by means of single photon emission tomography (SPET) in one patient before and after an auditory brainstem implant (...
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Article
Increased serum levels of soluble CD44 standard, but not of variant isoforms v5 and v6, in B cell chronic lymphocytic leukemia
The CD44 cell surface proteoglycan participates in a variety of functions including lymphohematopoiesis, lymphocyte homing and tumor metastasis. In addition to the standard form (CD44st), a large family of var...
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Article
T-helper phenotype chronic lymphocytic leukemia (Thp-CLL): Characterization of an Italian case with particular biological findings
A patient with Chronic Lymphocytic Leukemia (CLL) characterized by an expansion of helper phenotype mature T lymphocytes is here described. The phenotype of these cells was OKT3+, OKT4+, Leu 9+, 5/9+, OKT8−, Tac−
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Article
Decreased NK activity in hairy cell leukemia (HCL): An analysis at the cellular level
Peripheral blood lymphocytes (PBL) of eleven patients with Hairy Cell Leukemia were studied for surface phenotype and for NK activity against the K 562 cell line (using both the standard 51Cr Release Assay and th...
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Article
The particular usefulness of radioisotope methods in some benign bone diseases
The authors have performed radioisotope examinations in 271 patients with various non-neoplastic bone diseases.
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Article
Die Toleranz bei Hüftgelenkprothesen bewertet durch szintigraphische Studien
The authors assert the usefulness of the scintigraphy in the early diagnosis and/or for the confirmation of the main complications connected with the artroprosthesis of the hip. Such investigation is effective...
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Chapter
La détection des métastases intracraniennes par scintigraphie et gammacisternographie
Nous avons examinés 43 cas de métastases cérébrales, controlées par le cours clinique et les résultats opératoires et nécroscopiques.
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Article
Bestimmung der Mauerfeuchtigkeit