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  1. No Access

    Article

    Daratumumab in multiple myeloma: experience of the multiple myeloma GIMEMA Lazio group

    Daratumumab (DARA) is a human IgG-K monoclonal antibody (MoAb) targeting CD38 that is approved alone or in combination with bortezomib and dexamethasone or lenalidomide and dexamethasone for relapsed or refrac...

    Federico Vozella, A. Siniscalchi, M. Rizzo, T. Za, G. Antolino… in Annals of Hematology (2021)

  2. No Access

    Article

    Diagnostic and prognostic role of PET/CT in patients with chronic lymphocytic leukemia and progressive disease

    In order to evaluate the predictive value of positron emission tomography–computed tomography (PET/CT) in discriminating the presence of a Richter’s syndrome (RS) or a second malignancy (SM), as well as to eva...

    F R Mauro, S Chauvie, F Paoloni, A Biggi, G Cimino, A Rago, M Gentile… in Leukemia (2015)

  3. No Access

    Article

    Epigenetic plasticity of chromatin in embryonic and hematopoietic stem/progenitor cells: therapeutic potential of cell reprogramming

    During embryonic development and adult life, the plasticity and reversibility of modifications that affect the chromatin structure is important in the expression of genes involved in cell fate decisions and th...

    G Zardo, G Cimino, C Nervi in Leukemia (2008)

  4. No Access

    Article

    Occurrence of thrombotic events in acute promyelocytic leukemia correlates with consistent immunophenotypic and molecular features

    Although the occurrence of thrombosis in acute promyelocytic leukemia (APL) has been reported during retinoic acid treatment, no studies carried out in large clinical cohorts have specifically addressed this i...

    M Breccia, G Avvisati, R Latagliata, I Carmosino, A Guarini, M S De Propris… in Leukemia (2007)

  5. No Access

    Article

    CIZ gene rearrangements in acute leukemia: report of a diagnostic FISH assay and clinical features of nine patients

    R La Starza, A Aventin, B Crescenzi, P Gorello, G Specchia, A Cuneo, A Angioni… in Leukemia (2005)

  6. No Access

    Article

    BAVC regimen and autologous bone marrow transplantation for APL patients in second molecular remission: updated results

    S Capria, R Latagliata, G Avvisati, M Breccia, G Cimino… in Bone Marrow Transplantation (2005)

  7. No Access

    Article

    CD1d expression on B-precursor acute lymphoblastic leukemia subsets with poor prognosis

    Acute lymphoblastic leukemia (ALL) is the most frequent malignancy of childhood. Although therapeutical advances have been achieved, some ALL subgroups still fare poorly. CD1d is a monomorphic molecule that pr...

    F Fais, C Tenca, G Cimino, V Coletti, S Zanardi, D Bagnara, D Saverino… in Leukemia (2005)

  8. No Access

    Article

    Significant reduction of the hybrid BCR/ABL transcripts after induction and consolidation therapy is a powerful predictor of treatment response in adult Philadelphia-positive acute lymphoblastic leukemia

    Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) has a dismal prognosis. We prospectively evaluated minimal residual disease (MRD) by measuring BCR/ABL levels with a quantitative real-tim...

    F Pane, G Cimino, B Izzo, A Camera, A Vitale, C Quintarelli, M Picardi… in Leukemia (2005)

  9. No Access

    Article

    Biclonal blast crisis with a mutated ABL catalytic domain in a Ph, del (9q)-positive CML patient responsive to imatinib: drug resistance should be monitored in all patients irrespective of response status

    G Alimena, M Breccia, M Mancini, D Diverio, M Nanni, M S De Propris, G Cimino… in Leukemia (2005)

  10. No Access

    Article

    Retrospective comparison of qualitative and quantitative reverse transcriptase polymerase chain reaction in diagnosing and monitoring the ALL1-AF4 fusion transcript in patients with acute lymphoblastic leukaemia

    We compared quantitative reverse transcriptase polymerase chain reaction (Q-RT-PCR) to qualitative RT-PCR in determining response to therapy and predicting clinical outcome in 18 retrospectively selected patie...

    L Elia, E Gottardi, G Floriddia, R Grillo, F Ciambelli, M Luciani, P Chiusolo… in Leukemia (2004)

  11. No Access

    Article

    Quality Assessment of Freshwater and Coastal Seawater in the Ionian Area of N.E. Sicily, Italy

    This work was conducted to analyse pressing and competingdemands of water in Northeast Sicily, Italy. In thisarea, looking at the Ionian Sea, freshwaters and coastalseawaters have been studied on the quality a...

    G. Cimino, M. C. Puleio, G. Toscano in Environmental Monitoring and Assessment (2002)

  12. No Access

    Article

    Upregulation of Meis1 and HoxA9 in acute lymphocytic leukemias with the t(4 : 11) abnormality

    Rearrangements of the human ALL-1 gene are frequently encountered in acute lymphocytic leukemias (ALL) and acute myeloid leukemias (AML). These rearrangements are mostly due to chromosome translocations and re...

    T Rozovskaia, E Feinstein, O Mor, R Foa, J Blechman, T Nakamura, C M Croce… in Oncogene (2001)

  13. No Access

    Article

    Idarubicin intensified BUCY2 regimen in allogeneic unmanipulated transplant for high-risk hematological malignancies

    Twenty-nine consecutive patients with high-risk hematological malignancy aged from 3 to 58 years underwent an unmanipulated graft from an HLA-identical sibling after an irradiation-free preparative regimen con...

    A Mengarelli, AP Iori, C Guglielmi, MP Perrone, M Gozzer, C Girmenia, G Cimino… in Leukemia (2000)

  14. No Access

    Article

    HLA class I in acute promyelocytic leukemia (APL): possible correlation with clinical outcome

    The majority of patients with acute promyelocytic leukemia (APL) possess either a bcr1 or a bcr3 type fusion between PML and RARα genes. The junction sequences may possibly be a target for immune response and ...

    E Bolognesi, G Cimino, D Diverio, MC Rapanotti, S D'Alfonso, K Fleischhauer… in Leukemia (2000)

  15. No Access

    Article

    Outpatient management of acute promyelocytic leukemia after consolidation chemotherapy

    The feasibility and safety of outpatient management of acute promyelocytic leukemia (APL) during the aplastic phase after intensive consolidation chemotherapy, the incidence and types of complications requirin...

    C Girmenia, R Latagliata, S Tosti, SG Morano, F Celesti, L Coppola, A Spadea… in Leukemia (1999)

  16. No Access

    Article

    Umbilical cord blood transplant from unrelated HLA-mismatched donors in children with high risk leukemia

    In the last 3 years, 14 children with high-risk leukemia (11 ALL, 2 AML and 1 CML) underwent cord blood transplantation from unrelated HLA-mismatched donors at a median of 99 days from the start of search. Eig...

    W Arcese, C Guglielmi, AP Iori, M Screnci, D Carmini… in Bone Marrow Transplantation (1999)

  17. No Access

    Article

    Sequential molecular monitoring of chimerism in chronic myeloid leukemia patients receiving donor lymphocyte transfusion for relapse after bone marrow transplantation

    Recent observations of chimerism in patients relapsed following an allotransplant suggest the persistence of immunotolerance, thus offering a biologic rationale for the use of donor lymphocyte transfusion (DLT...

    MC Rapanotti, W Arcese, S Buffolino, AP Iori, A Mengarelli… in Bone Marrow Transplantation (1997)

  18. No Access

    Article

    Novel diterpenoid diacylglycerols from marine molluscs: potent morphogens and protein kinase C activators

    Five novel 1,2-sn-diacylglycerols with diterpenoid acyl moieties in thesn-1 position were isolated and characterized, together with the corresponding 1,3-sn-diacylglycerols, from three species of dorid nudibranch...

    L. De Petrocellis, P. Orlando, M. Gavagnin, M. Ventriglia, G. Cimino… in Experientia (1996)

  19. No Access

    Article

    Occurrence and biosynthesis of 11 (R)-hydroxy-eicosatetraenoic acid (11-R-HETE) in the Caribbean soft coralPlexaurella dichotoma

    Gorgonian soft corals from the Caribbean Sea are known to contain prostaglandin-like compounds as well as other products of arachidonic acid lipoxygenation, and the formation of the latter has been suggested t...

    V. Di Marzo, M. Ventriglia, E. Mollo, M. Mosca, G. Cimino in Experientia (1996)

  20. No Access

    Article

    PrecipitatingPseudomonas aeruginosa antibodies and antimicrobial therapy in cystic fibrosis patients

    Forty patients with cystic fibrosis were studied bacteriologically and serologically. PrecipitatingPseudomonas aeruginosa antibodies were monitored by crossed-immunoelectrophoresis (CIE) in order to evaluate the ...

    M. Trancassini, D. de Vito, G. Cimino… in European Journal of Clinical Microbiology … (1996)

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