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Article
Polycythemia vera treated with pipobroman as single agent: low incidence of secondary leukemia in a cohort of patients observed during 20 years (1971–1991)
The ‘gold standard’ for the treatment of polycythemia vera (PV) is to date undefined. We performed a retrospective analysis to evaluate the outcome of a cohort of PV patients treated with pipobroman (PB) at a ...
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Article
Mediastinal extramedullary hematopoiesis as first manifestation of hereditary spherocytosis
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Article
T-helper phenotype chronic lymphocytic leukemia (Thp-CLL): Characterization of an Italian case with particular biological findings
A patient with Chronic Lymphocytic Leukemia (CLL) characterized by an expansion of helper phenotype mature T lymphocytes is here described. The phenotype of these cells was OKT3+, OKT4+, Leu 9+, 5/9+, OKT8−, Tac−
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Autologous Bone Marrow Transplantation (ABMT) for Patients with Chronic Granulocytic Leukemia (CGL) in Blastic Phase (BP)
Autologous hemopoietic stem cell infusion after high dose chemo/radiotherapy performed in BP of CGL is able to reinduce II CP in 90% of patients; however the median survival does not last more than 6 months. T...
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Article
POLYMORPHONUCLEAR LEUKOCYTES (PMN) TRANSFUSION FOR THE TREATMENT OF NEONATAL SEPSIS
25 newborns with bacterial sepsis received from 2 to 14 transfusions (20 ml/kg of a suspension containing .5-1 × 109 PMNs, and less than 6% lymphocytes, obtained by continuous flow filtration leukapheresis). Resu...
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Article
Functional activity of packed polymorphonuclear leukocytes (PMN) obtained by leukafiltration: 85
We recently obtained a striking increase of the survival rate in very small pre-term infants with sepsis through dayly transfusions of packed PMN (20ml/Kg equal to 0.5 × 1010 cells). In order to increase the avai...