12 Result(s)

Article

Interferon-γ-induced neuronal differentiation of human umbilical cord blood-derived progenitors

Human umbilical cord blood (HUCB) provides a source of progenitors for cell therapy. We isolated and characterized an HUCB-derived population of progenitors (HUCBNP), differentiated toward neuronal phenotype b...

H Arien-Zakay, S Lecht, M M Bercu, N Amariglio, G Rechavi, H Galski… in Leukemia (2009)

Article

The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation

The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, participate in the retention of acute myeloblastic leukemia (AML) cells within the bone marrow microenvironment and their release in...

S Tavor, M Eisenbach, J Jacob-Hirsch, T Golan, I Petit, K BenZion, S Kay… in Leukemia (2008)

Article

The presence of a single PML-RARA isoform lacking exon 5 in FISH-negative APL samples

O Ashur-Fabian, L Trakhtenbrot, D Dominissini, M Koren-Michowitz, A Nagler… in Leukemia (2008)

Article

High-throughput, sensitive and quantitative assay for the detection of BCR-ABL kinase domain mutations

A Vivante, N Amariglio, M Koren-Michowitz, O Ashur-Fabian, A Nagler, G Rechavi… in Leukemia (2007)

Article

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

Tumors contain a fraction of cancer stem cells that maintain the propagation of the disease. The CD34+CD38− cells, isolated from acute myeloid leukemia (AML), were shown to be enriched leukemic stem cells (LSC...

H Gal, N Amariglio, L Trakhtenbrot, J Jacob-Hirsh, O Margalit, A Avigdor… in Leukemia (2006)

Article

Chimerism testing and detection of minimal residual disease after allogeneic hematopoietic transplantation using the bioView (Duet™) combined morphological and cytogenetical analysis

Recurrent disease remains a major obstacle to cure after allogeneic transplantation. Various methods have been developed to detect minimal residual disease (MRD) after transplantation to identify patients at r...

A Shimoni, A Nagler, C Kaplinsky, M Reichart, A Avigdor, I Hardan, M Yeshurun… in Leukemia (2002)

Article

The clinical and biological dilemma of preleukemia presenting as aplastic anemia with chromosomal translocation t(4;11)

U Tabori, Y Burstein, R Dvir, G Rechavi, A Toren in Leukemia (2001)

Article

Early fulminant leukaemia post autologous bone marrow transplantation in non-hodgkin’s lymphoma patients

Although autologous bone marrow transplantation (ABMT) is a curative option for about 50% of the patients with progressive or relapsing Symphomas, considerable concern has been raised recently over the emergin...

A Toren, G Rechavi, A Nagler in Medical Oncology (1998)

Chapter and Conference Paper

PCR as a Diagnostic Tool in ALL: A Comparison Between Cytogenetic and Polymerase Chain Reaction Analysis in Pediatric Patients with Acute Lymphoblastic Leukemia

The E2A/PBXl and the BCR/ ABL fusion genes are formed by the t(l; 19)(q23;p13) and the t(9; 22)(q34; q 11), respectively, and encode oncoproteins which are thought to play an important role in the development ...

S. Izraeli, J. W. G. Janssen, O. A. Haas, J. Harbott, F. Brok-Simoni… in Acute Leukemias IV (1994)

Chapter and Conference Paper

Successful Central Nervous System Prophylaxis Without Radiotherapy in Childhood Acute Lymphoblastic Leukemia (ALL); Israel National Studies (INS 1984, 1989)

Adequate early prophylactic treatment for occult central-nervous-system (CNS) leukemia is one of the key elements for successful treatment in childhood acute lymphoblastic leukemia (ALL). The classical treatme...

B. Stark, A. Abromov, D. Attias, A. Balin, Y. Barak, Y. Goshen… in Acute Leukemias IV (1994)

Article

The management of pediatric brain tumors in a tertiary center

Between January 1982 and January 1990,120 newly diagnosed pediatric patients were treated at The Chaim Sheba Medical Center. Sixty three (52.5%) tumors arose in the posterior fossa and 57 (47.5%) appeared supr...

M. Mandel, A. Toren, G. Findler, Y. Neumann… in Medical Oncology and Tumor Pharmacotherapy (1992)