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Article
Open AccessMagnetic Resonance Imaging and Bioluminescence Imaging for Evaluating Tumor Burden in Orthotopic Colon Cancer
Quantifying tumor burden is important for following the natural history of orthotopic colon cancer and therapeutic efficacy. Bioluminescence imaging (BLI) is commonly used for such assessment and has both adva...
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Article
Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells
Tumors contain a fraction of cancer stem cells that maintain the propagation of the disease. The CD34+CD38− cells, isolated from acute myeloid leukemia (AML), were shown to be enriched leukemic stem cells (LSC...
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Article
Open AccessOverexpression of a set of genes, including WISP-1, common to pulmonary metastases of both mouse D122 Lewis lung carcinoma and B16-F10.9 melanoma cell lines
Despite advances in the management of solid tumours, the development of metastases continues to be the most significant problem and cause of death for cancer patients. To define genetic determinants of pulmona...