19 Result(s)

Article

Specific self-antigen-driven immune response in pericardial effusion as an isolated GVHD manifestation

Pericardial effusion and cardiac tamponade have been described as GVHD manifestations in the post transplant period. Direct evidence of GVHD-related TCR or B-cell receptor clones in patients with pericardial e...

A Lev, N Amariglio, Z Spirer, U Katz, B Bielorai, G Rechavi… in Bone Marrow Transplantation (2010)

Article

Interferon-γ-induced neuronal differentiation of human umbilical cord blood-derived progenitors

Human umbilical cord blood (HUCB) provides a source of progenitors for cell therapy. We isolated and characterized an HUCB-derived population of progenitors (HUCBNP), differentiated toward neuronal phenotype b...

H Arien-Zakay, S Lecht, M M Bercu, N Amariglio, G Rechavi, H Galski… in Leukemia (2009)

Article

The CXCR4 antagonist AMD3100 impairs survival of human AML cells and induces their differentiation

The chemokine stromal cell-derived factor-1 (SDF-1) and its receptor, CXCR4, participate in the retention of acute myeloblastic leukemia (AML) cells within the bone marrow microenvironment and their release in...

S Tavor, M Eisenbach, J Jacob-Hirsch, T Golan, I Petit, K BenZion, S Kay… in Leukemia (2008)

Article

The presence of a single PML-RARA isoform lacking exon 5 in FISH-negative APL samples

O Ashur-Fabian, L Trakhtenbrot, D Dominissini, M Koren-Michowitz, A Nagler… in Leukemia (2008)

Article

High-throughput, sensitive and quantitative assay for the detection of BCR-ABL kinase domain mutations

A Vivante, N Amariglio, M Koren-Michowitz, O Ashur-Fabian, A Nagler, G Rechavi… in Leukemia (2007)

Article

Gene expression profiles of AML derived stem cells; similarity to hematopoietic stem cells

Tumors contain a fraction of cancer stem cells that maintain the propagation of the disease. The CD34+CD38− cells, isolated from acute myeloid leukemia (AML), were shown to be enriched leukemic stem cells (LSC...

H Gal, N Amariglio, L Trakhtenbrot, J Jacob-Hirsh, O Margalit, A Avigdor… in Leukemia (2006)

Article

Multilineage hematopoietic engraftment after allogeneic peripheral blood stem cell transplantation without conditioning in SCID patients

Successful stem cell transplantation for patients with severe combined immunodeficiency (SCID) from matched family donors without conditioning results in engraftment of T lymphocytes. B lymphocytes engraft in ...

B Bielorai, L Trakhtenbrot, N Amariglio, R Rothman, U Tabori… in Bone Marrow Transplantation (2004)

Article

Tetraploid myeloid cells in donors of peripheral blood stem cells treated with rhG-CSF

Recombinant human granulocyte colony-stimulating factor (rhG-CSF) is frequently used to mobilize CD34+ cells in healthy donors and patient with malignant diseases prior to peripheral blood stem cell (PBSC) har...

C Kaplinsky, L Trakhtenbrot, I Hardan, M Reichart, M Daniely… in Bone Marrow Transplantation (2003)

Article

B-cell lymphoma develo** in the donor 9 years after donor-origin acute myeloid leukemia post bone marrow transplantation

Donor-cell leukemia post bone marrow transplantation is a rare event. Most of the cases reported to date have developed in cells from an HLA-matched sibling, who had no evidence of malignant disease before or ...

B Bielorai, H J Deeg, M Weintraub, Y Neumann, E Rosner… in Bone Marrow Transplantation (2003)

Article

Chimerism testing and detection of minimal residual disease after allogeneic hematopoietic transplantation using the bioView (Duet™) combined morphological and cytogenetical analysis

Recurrent disease remains a major obstacle to cure after allogeneic transplantation. Various methods have been developed to detect minimal residual disease (MRD) after transplantation to identify patients at r...

A Shimoni, A Nagler, C Kaplinsky, M Reichart, A Avigdor, I Hardan, M Yeshurun… in Leukemia (2002)

Article

CMV reactivation induced BK virus-associated late onset hemorrhagic cystitis after peripheral blood stem cell transplantation

Hemorrhagic cystitis (HC) is a known complication of stem cell transplantation. In contrast to early-onset HC that is usually attributed to cyclophosphamide and occurs within a few days of infusion, late onset...

B Bielorai, LM Shulman, G Rechavi, A Toren in Bone Marrow Transplantation (2001)

Article

The clinical and biological dilemma of preleukemia presenting as aplastic anemia with chromosomal translocation t(4;11)

U Tabori, Y Burstein, R Dvir, G Rechavi, A Toren in Leukemia (2001)

Article

Successful treatment of invasive aspergillosis in chronic granulomatous disease by granulocyte transfusions followed by peripheral blood stem cell transplantation

Chronic granulomatous disease (CGD) is a primary immunodeficiency disorder characterized by impaired microbial killing and susceptibility to bacterial and fungal infections. Cure of the disease can be achieved...

B Bielorai, A Toren, B Wolach, M Mandel, H Golan, Y Neumann… in Bone Marrow Transplantation (2000)

Article

Successful human umbilical cord blood stem cell transplantation without conditioning in severe combined immune deficiency

A 2-month-old girl with severe combined immunodeficiency (SCID), presented with mild staphylococcal skin infection, lymphopenia, low T cell number, absence of B cells, high number of NK cells, and a negligible...

A Toren, A Nagler, N Amariglio, Y Neumann, H Golan, B Bilori… in Bone Marrow Transplantation (1999)

Article

Early fulminant leukaemia post autologous bone marrow transplantation in non-hodgkin’s lymphoma patients

Although autologous bone marrow transplantation (ABMT) is a curative option for about 50% of the patients with progressive or relapsing Symphomas, considerable concern has been raised recently over the emergin...

A Toren, G Rechavi, A Nagler in Medical Oncology (1998)

Chapter and Conference Paper

PCR as a Diagnostic Tool in ALL: A Comparison Between Cytogenetic and Polymerase Chain Reaction Analysis in Pediatric Patients with Acute Lymphoblastic Leukemia

The E2A/PBXl and the BCR/ ABL fusion genes are formed by the t(l; 19)(q23;p13) and the t(9; 22)(q34; q 11), respectively, and encode oncoproteins which are thought to play an important role in the development ...

S. Izraeli, J. W. G. Janssen, O. A. Haas, J. Harbott, F. Brok-Simoni… in Acute Leukemias IV (1994)

Chapter and Conference Paper

Successful Central Nervous System Prophylaxis Without Radiotherapy in Childhood Acute Lymphoblastic Leukemia (ALL); Israel National Studies (INS 1984, 1989)

Adequate early prophylactic treatment for occult central-nervous-system (CNS) leukemia is one of the key elements for successful treatment in childhood acute lymphoblastic leukemia (ALL). The classical treatme...

B. Stark, A. Abromov, D. Attias, A. Balin, Y. Barak, Y. Goshen… in Acute Leukemias IV (1994)

Article

The management of pediatric brain tumors in a tertiary center

Between January 1982 and January 1990,120 newly diagnosed pediatric patients were treated at The Chaim Sheba Medical Center. Sixty three (52.5%) tumors arose in the posterior fossa and 57 (47.5%) appeared supr...

M. Mandel, A. Toren, G. Findler, Y. Neumann… in Medical Oncology and Tumor Pharmacotherapy (1992)