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  1. Article

    Open Access

    CGRP-targeted medication in chronic migraine - systematic review

    Chronic migraine is a highly debilitating condition that is often difficult to manage, particularly in the presence of medication overuse headache. Drugs targeting the calcitonin gene-related peptide (CGRP), o...

    Renato Oliveira, Raquel Gil-Gouveia, Francesca Puledda in The Journal of Headache and Pain (2024)

  2. Article

    Open Access

    Health equity, care access and quality in headache – part 2

    Headache disorders are a global public health concern affecting diverse populations. This review examines headache service organizations in low-, middle-, and high-income countries. It addresses global challen...

    Bianca Raffaelli, Eloísa Rubio-Beltrán, Soo-** Cho in The Journal of Headache and Pain (2023)

  3. Article

    Open Access

    Visual snow syndrome and migraine: a review

    Visual snow syndrome is a neurological condition characterized by ongoing prominent phenomena described consistently as tiny dots moving across the entire visual field, often associated with complex visual sym...

    Elisa Martins Silva, Francesca Puledda in Eye (2023)

  4. Article

    Open Access

    Migraine: from pathophysiology to treatment

    Migraine is an extremely disabling, common neurological disorder characterized by a complex neurobiology, involving a series of central and peripheral nervous system areas and networks. A growing increase in t...

    Francesca Puledda, Elisa Martins Silva, Kanokrat Suwanlaong in Journal of Neurology (2023)

  5. Article

    Open Access

    Neurophysiological correlates of clinical improvement after greater occipital nerve (GON) block in chronic migraine: relevance for chronic migraine pathophysiology

    Therapeutic management of Chronic Migraine (CM), often associated with Medication Overuse Headache (MOH), is chiefly empirical, as no biomarker predicting or correlating with clinical efficacy is available to ...

    Alessandro Viganò, Maria Claudia Torrieri in The Journal of Headache and Pain (2018)

  6. Article

    Open Access

    Treatment of disabling headache with greater occipital nerve injections in a large population of childhood and adolescent patients: a service evaluation

    Pediatric headache disorders can be extremely disabling, with marked reduction in the quality of life of children and their carers. Evidenced-based options for the treatment of primary headache disorders with ...

    Francesca Puledda, Peter J. Goadsby, Prab Prabhakar in The Journal of Headache and Pain (2018)

  7. Article

    Open Access

    An update on migraine: current understanding and future directions

    Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase i...

    Francesca Puledda, Roberta Messina, Peter J. Goadsby in Journal of Neurology (2017)

  8. Article

    Open Access

    Current Approaches to Neuromodulation in Primary Headaches: Focus on Vagal Nerve and Sphenopalatine Ganglion Stimulation

    Neuromodulation is a promising, novel approach for the treatment of primary headache disorders. Neuromodulation offers a new dimension in the treatment that is both easily reversible and tends to be very well ...

    Francesca Puledda, Peter J. Goadsby in Current Pain and Headache Reports (2016)

  9. No Access

    Article

    A study of migraine characteristics in joint hypermobility syndrome a.k.a. Ehlers–Danlos syndrome, hypermobility type

    Joint hypermobility syndrome (JHS) and Ehlers–Danlos syndrome, hypermobility type (EDS-HT) are two clinically overlap** heritable connective tissue disorders strongly associated with musculoskeletal pain, fa...

    Francesca Puledda, Alessandro Viganò, Claudia Celletti in Neurological Sciences (2015)

  10. Article

    Open Access

    Topiramate modulates habituation in migraine: evidences from nociceptive responses elicited by laser evoked potentials

    Lack of habituation during repetitive stimulation is the most consistent interictal abnormality of cortical information processing observed in migraine. Preventive migraine treatments might act by stabilizing ...

    Laura Di Clemente, Francesca Puledda in The Journal of Headache and Pain (2013)