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Article
Open AccessCGRP-targeted medication in chronic migraine - systematic review
Chronic migraine is a highly debilitating condition that is often difficult to manage, particularly in the presence of medication overuse headache. Drugs targeting the calcitonin gene-related peptide (CGRP), o...
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Article
Open AccessHealth equity, care access and quality in headache – part 2
Headache disorders are a global public health concern affecting diverse populations. This review examines headache service organizations in low-, middle-, and high-income countries. It addresses global challen...
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Article
Open AccessVisual snow syndrome and migraine: a review
Visual snow syndrome is a neurological condition characterized by ongoing prominent phenomena described consistently as tiny dots moving across the entire visual field, often associated with complex visual sym...
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Article
Open AccessMigraine: from pathophysiology to treatment
Migraine is an extremely disabling, common neurological disorder characterized by a complex neurobiology, involving a series of central and peripheral nervous system areas and networks. A growing increase in t...
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Article
Open AccessNeurophysiological correlates of clinical improvement after greater occipital nerve (GON) block in chronic migraine: relevance for chronic migraine pathophysiology
Therapeutic management of Chronic Migraine (CM), often associated with Medication Overuse Headache (MOH), is chiefly empirical, as no biomarker predicting or correlating with clinical efficacy is available to ...
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Article
Open AccessNon-Pharmacological Approaches for Migraine
Migraine is one of the most common and debilitating neurological disorders. However, the efficacy of pharmacological therapies may have unsatisfactory efficacy and can be poorly tolerated. There is a strong ne...
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Article
Open AccessTreatment of disabling headache with greater occipital nerve injections in a large population of childhood and adolescent patients: a service evaluation
Pediatric headache disorders can be extremely disabling, with marked reduction in the quality of life of children and their carers. Evidenced-based options for the treatment of primary headache disorders with ...
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Article
Open AccessAn update on migraine: current understanding and future directions
Migraine is a common brain disorder with high disability rates which involves a series of abnormal neuronal networks, interacting at different levels of the central and peripheral nervous system. An increase i...
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Article
Open AccessCurrent Approaches to Neuromodulation in Primary Headaches: Focus on Vagal Nerve and Sphenopalatine Ganglion Stimulation
Neuromodulation is a promising, novel approach for the treatment of primary headache disorders. Neuromodulation offers a new dimension in the treatment that is both easily reversible and tends to be very well ...
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Article
A study of migraine characteristics in joint hypermobility syndrome a.k.a. Ehlers–Danlos syndrome, hypermobility type
Joint hypermobility syndrome (JHS) and Ehlers–Danlos syndrome, hypermobility type (EDS-HT) are two clinically overlap** heritable connective tissue disorders strongly associated with musculoskeletal pain, fa...
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Article
Open AccessTopiramate modulates habituation in migraine: evidences from nociceptive responses elicited by laser evoked potentials
Lack of habituation during repetitive stimulation is the most consistent interictal abnormality of cortical information processing observed in migraine. Preventive migraine treatments might act by stabilizing ...