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    Article

    Quantification of perineural invasion in pancreatic ductal adenocarcinoma: proposal of a severity score system

    Perineural invasion (PNI) is a common feature in pancreatic ductal adenocarcinoma (PDAC) and correlates with an aggressive tumor behavior already at early stages of disease. PNI is currently considered as a “p...

    Marco Schiavo Lena, Giulia Gasparini, Stefano Crippa, Giulio Belfiori in Virchows Archiv (2023)

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    Article

    Pancreatic metastases after surgery for renal cell carcinoma: survival and pathways of progression

    Metastatic ccRCC has peculiar tropism in the pancreas. We describe the characteristics and pathways of progression of patients with PM in a large multi-institutional consortium and compare them to patients wit...

    Daniele Cignoli, Giuseppe Fallara, Francesca Aleotti in World Journal of Urology (2022)

  3. Article

    Cellular and transcriptional dynamics of human neutrophils at steady state and upon stress

    Traditionally viewed as poorly plastic, neutrophils are now recognized as functionally diverse; however, the extent and determinants of neutrophil heterogeneity in humans remain unclear. We performed a compreh...

    Elisa Montaldo, Eleonora Lusito, Valentina Bianchessi in Nature Immunology (2022)

  4. Article

    Correction to: Total pancreatectomy sequelae and quality of life: results of islet autotransplantation as a possible mitigation strategy

    Francesca Aleotti, Rita Nano, Lorenzo Piemonti, Massimo Falconi in Updates in Surgery (2021)

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    Article

    Re-laparoscopy in the treatment of anastomotic leak following laparoscopic right colectomy with intracorporeal anastomosis

    Anastomotic leak still represents the most feared surgical complication following colorectal resection and is associated with high morbidity and mortality rates. The aim of this study is to assess the feasibil...

    Andrea Vignali, Ugo Elmore, Francesca Aleotti, Delpini Roberto in Surgical Endoscopy (2021)

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    Article

    Total pancreatectomy sequelae and quality of life: results of islet autotransplantation as a possible mitigation strategy

    Total pancreatectomy (TP) is a procedure weighed down not only by postoperative morbidity and mortality but also by long-term effects as a consequence of endocrine and exocrine pancreatic insufficiency. While ...

    Francesca Aleotti, Rita Nano, Lorenzo Piemonti, Massimo Falconi in Updates in Surgery (2021)

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    Minimally Invasive Pancreatectomy plus Islet Autotransplantation for Benign Tumors of the Pancreatic Neck and Body

    Francesca Aleotti, Rita Nano, Paola Maffi in Minimally Invasive Surgery of the Pancreas (2018)

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    Article

    Insulin resistance is associated with the aggressiveness of pancreatic ductal carcinoma

    To study whether insulin resistance accelerates the development and/or the progression of pancreatic adenocarcinoma (PDAC), we hypothesized that patients with insulin resistance, compared with those without in...

    Erica Dugnani, Gianpaolo Balzano, Valentina Pasquale, Marina Scavini in Acta Diabetologica (2016)

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    Article

    Treatment of branch-duct intraductal papillary mucinous neoplasms of the pancreas: state of the art

    The diagnosis of branch-duct intraductal papillary mucinous neoplasms (BD-IPMNs) has been dramatically increased. BD-IPMNs are frequently discovered as incidental findings in asymptomatic individuals, mainly i...

    Stefano Crippa, Alessandra Piccioli, Maria Chiara Salandini in Updates in Surgery (2016)

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    Article

    Diabetes After Pancreatic Surgery: Novel Issues

    In the developed world, pancreatic surgery is becoming more common, with an increasing number of patients develo** diabetes because of either partial or total pancreatectomy, with a significant impact on qua...

    Marina Scavini, Erica Dugnani, Valentina Pasquale in Current Diabetes Reports (2015)