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Article
Response to comment on: Long-term outcomes of penile squamous cell carcinoma in men age ≤50 years old compared with men >50 years old
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Article
Long-term functional outcomes in patients undergoing radical nephrectomy for renal cell carcinoma and tumor thrombus
Up to 15% of patients with locally advanced renal cell carcinoma (RCC) harbors tumor thrombus (TT). In those cases, radical nephrectomy (RN) and thrombectomy represents the standard of care. We assessed the im...
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Article
Intraoperative image-guidance during robotic surgery: is there clinical evidence of enhanced patient outcomes?
To date, the benefit of image guidance during robot-assisted surgery (IGS) is an object of debate. The current study aims to address the quality of the contemporary body of literature concerning IGS in robotic...
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Article
Open AccessLong-term outcomes of penile squamous cell carcinoma in men age ≤50 years old compared with men >50 years old from a single tertiary referral centre: a propensity score matched analysis
Penile cancer (PeCa) is rare, and the oncological outcomes in younger men are unclear. We aimed to analyse and compare oncological outcomes of men age ≤50 years (y) and >50 years with PeCa. A retrospective ana...
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Article
Medications mostly associated with priapism events: assessment of the 2015–2020 Food and Drug Administration (FDA) pharmacovigilance database entries
A range of drugs have a direct role in triggering ischaemic priapism. We aimed at identifying: a) which medications are associated with most priapism-reports; and, b) within these medications, comparing their ...
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Article
Prevalence and predictors of unrecognised low sexual desire/interest in men with new onset erectile dysfunction: findings from a cross-sectional, real-life study
The interrelationship between male sexual desire and erectile dysfunction (ED) has been scantly investigated. Thus, we aimed at investigating the prevalence of and the predictors of unrecognised low sexual des...
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Article
Premature ejaculation among men with erectile dysfunction—findings from a real-life cross-sectional study
Concomitant sexual disorders have progressively shown increased prevalence in men at first outpatient presentation. We sought to i) estimate the prevalence of unreported premature ejaculation (PE) in a homogen...
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Article
Oncological and perioperative outcomes of surgery with or without metastasis-directed therapy as part of a multimodal treatment in men with de-novo oligometastatic prostate cancer
To investigate the feasibility, safety, and oncological outcomes of Radical Prostatectomy (RP; either Robot-Assisted [RARP] or Open RP [ORP]) in oligometastatic prostate cancer (omPCa). Additionally, we assess...
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Article
Are finasteride-related penile curvature/Peyronie’s disease Adverse Event Reports worthy of further clinical investigation? Disproportionality analysis based on both the Food and Drug Administration (FDA) and the European Medicines Agency (EMA) pharmacovigilance databases
A limited number of studies have described patients on finasteride showing findings which were consistent with Peyronie’s disease (PD). We aimed to detect a pharmacovigilance signal of possible association bet...
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Article
Neglected lymph nodal metastases in patients with renal cancer: when to extend the anatomical template of lymph node dissection during nephrectomy
The role of lymph node dissection (LND) in patients with renal cell carcinoma (RCC) is still controversial. However, detecting lymph node invasion (LNI) is key due to prognostic implications and to identify pa...
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Article
Outcomes following radical inguinal lymphadenectomy for penile cancer using a fascial-sparing surgical technique
To describe our surgical technique and report the oncological outcomes and complication rates using a fascial-sparing radical inguinal lymphadenectomy (RILND) technique for penile cancer patients with cN+ dise...
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Article
Open AccessThe retinal neurovascular coupling is impaired in men with vasculogenic erectile dysfunction
The aim of this study was to study the retinal vessels in patients affected by vasculogenic erectile dysfunction (ED), using dynamic vessel analyzer (DVA). Patients with vasculogenic ED and control subjects we...
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Article
Open AccessComplications and outcomes following injection of foreign material into the male external genitalia for augmentation: a single-centre experience and systematic review
Injection of exogenous material into the penis and scrotum has been performed for augmentation purposes. Complications include cosmetic dissatisfaction, penile necrosis and lymphoedema. We report the complicat...
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Chapter
How to Manage the Lymph Nodes in Penile Cancer
The presence of metastatic disease within the inguinal lymph nodes represents the most important prognostic indicator for men with penile cancer. In penile cancer metastatic spread typically follows a stepwise...
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Chapter
Orgasm and Ejaculation Disorders
Disorders of ejaculations are among the most complex complaints of patients seeking first medical help for sexual dysfunction. Among these, premature ejaculation (PE), delayed ejaculation (DE), retrograde ejac...
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Article
How to optimize the use of adjuvant pembrolizumab in renal cell carcinoma: which patients benefit the most?
The KEYNOTE-564 trial showed improved disease-free survival (DFS) for patients with high-risk renal cell carcinoma (RCC) receiving adjuvant pembrolizumab as compared to placebo. However, if systematically admi...
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Article
Pancreatic metastases after surgery for renal cell carcinoma: survival and pathways of progression
Metastatic ccRCC has peculiar tropism in the pancreas. We describe the characteristics and pathways of progression of patients with PM in a large multi-institutional consortium and compare them to patients wit...
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Article
Real-life use of the eutectic mixture lidocaine/prilocaine spray in men with premature ejaculation
Topical anaesthetics are considered a first-line therapy option in men with premature ejaculation (PE). A cross-sectional retrospective analysis was performed to evaluate the real-life use of the eutectic mixt...
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Article
Parenchymal biopsy in the management of patients with renal cancer
The role of non-tumour renal biopsy in predicting renal function after surgery for renal cell carcinoma (RCC) is poorly investigated. The aim of the study was to assess the impact of renal parenchymal histolog...
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Article
The impact of intraoperative bleeding on the risk of chronic kidney disease after nephron-sparing surgery
The current literature regarding the effect of blood loss (eBL) after nephron-sparing surgery (NSS) on long-term renal function is scarce. We tested the effect of eBL on the risk of develo** chronic kidney d...