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Article
Open AccessPoMeLo: a systematic computational approach to predicting metabolic loss in pathogen genomes
Genome streamlining, the process by which genomes become smaller and encode fewer genes over time, is a common phenomenon among pathogenic bacteria. This reduction is driven by selection for minimized energy e...
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Article
Open AccessConverting non-neutralizing SARS-CoV-2 antibodies into broad-spectrum inhibitors
Omicron and its subvariants have rendered most authorized monoclonal antibody-based treatments for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ineffective, highlighting the need for biologics ...
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Article
Convergent antibody responses to SARS-CoV-2 in convalescent individuals
During the coronavirus disease-2019 (COVID-19) pandemic, severe acute respiratory syndrome-related coronavirus-2 (SARS-CoV-2) has led to the infection of millions of people and has claimed hundreds of thousand...
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Article
Future distribution of tundra refugia in northern Alaska
Climate change in the Arctic is a growing concern for natural resource conservation and management as a result of accelerated warming and associated shifts in the distribution and abundance of northern species...