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  1. Article

    Open Access

    PoMeLo: a systematic computational approach to predicting metabolic loss in pathogen genomes

    Genome streamlining, the process by which genomes become smaller and encode fewer genes over time, is a common phenomenon among pathogenic bacteria. This reduction is driven by selection for minimized energy e...

    Abigail Glascock, Eric Waltari, Gytis Dudas, Joan Wong, Vida Ahyong in BMC Bioinformatics (2024)

  2. Article

    Open Access

    The antibiotic resistance reservoir of the lung microbiome expands with age in a population of critically ill patients

    Antimicrobial resistant lower respiratory tract infections are an increasing public health threat and an important cause of global mortality. The lung microbiome can influence susceptibility of respiratory tra...

    Victoria T. Chu, Alexandra Tsitsiklis, Eran Mick in Nature Communications (2024)

  3. Article

    Open Access

    Detection of SARS-CoV-2 RNA using RT-LAMP and molecular beacons

    Rapid spread of SARS-CoV-2 has led to a global pandemic, resulting in the need for rapid assays to allow diagnosis and prevention of transmission. Reverse transcription-polymerase chain reaction (RT-PCR) provi...

    Scott Sherrill-Mix, Young Hwang, Aoife M. Roche, Abigail Glascock in Genome Biology (2021)