-
Article
Open AccessSubcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials
We conducted a systematic review and network meta-analysis to compare the efficacy and safety of s.c. administered tirzepatide vs s.c. administered semaglutide for adults of both sexes with type 2 diabetes mel...
-
Article
Open AccessManagement of type 2 diabetes in the new era
Management of type 2 diabetes is advancing beyond glycemic control and is increasingly based on cardiovascular risk stratification. This review summarizes recent advances in the field and identifies existing k...
-
Article
Open AccessComparative efficacy of glucose-lowering drugs on liver steatosis as assessed by means of magnetic resonance imaging in patients with type 2 diabetes mellitus: systematic review and network meta-analysis
To assess the comparative efficacy of glucose-lowering drugs on liver steatosis as assessed by means of magnetic resonance imaging (MRI) in patients with T2D.
-
Article
Open AccessSocioeconomic aspects of incretin-based therapy
Incretin-based therapies, particularly glucagon-like peptide-1 receptor agonists (GLP-1 RAs), have demonstrated cardiovascular benefits in people with type 2 diabetes. However, socioeconomic disparities in the...
-
Chapter
Teaching Humanities Through Digital Tools in Secondary Education
Towards the milestones skills of a successful learner at any age and the four C’s (critical thinking, collaboration, creativity and communication), a goal for teachers is to go beyond fact memorization and to ...
-
Article
Open AccessManagement of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis
Tirzepatide is a novel dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) currently under review for marketing approval. Individual trials have assessed...
-
Chapter
Long-Term Maternal Complications
Overt diabetes mellitus during pregnancy is associated with substantial adverse outcomes both for maternal and neonatal health. Women with gestational diabetes face an increased risk for future development of ...
-
Article
Fixed ratio combinations of glucagon like peptide 1 receptor agonists with basal insulin: a systematic review and meta-analysis
Basal insulin controls primarily fasting plasma glucose but causes hypoglycaemia and weight gain, whilst glucagon like peptide 1 receptor agonists induce weight loss without increasing risk for hypoglycaemia. ...
-
Article
Arterial stiffness and peripheral arterial disease in patients with systemic lupus erythematosus
Systemic lupus erythematosus (SLE) is associated with increased cardiovascular risk. We aimed to evaluate arterial stiffness and the ankle brachial index (ABI), two markers of subclinical cardiovascular diseas...
-
Article
Antigen-based immunotherapies do not prevent progression of recent-onset autoimmune diabetes: a systematic review and meta-analysis
We performed a systematic review and meta-analysis to assess the efficacy and safety of antigen-based immunotherapies in tertiary prevention of autoimmune diabetes. We searched for randomised controlled trials...
-
Article
Systematic review and meta-analysis of vildagliptin for treatment of type 2 diabetes
This systematic review and meta-analysis provides an update on the efficacy and safety of vildagliptin for treatment of type 2 diabetes mellitus (T2DM). We searched MEDLINE, COCHRANE, EMBASE and the drug manuf...
-
Article
Sodium-Glucose Cotransporter 2 Inhibition and Cardiovascular Risk
The choice of appropriate therapy for patients with type 2 diabetes is currently based on the effect of available pharmacologic agents on metabolic parameters. Beyond metformin, much uncertainty remains about ...
-
Article
Premixed insulin regimens for type 2 diabetes
-
Article
Eosinophilic pneumonia associated with heroin inhalation: a case report
Medikamente sind eine bekannte Ursache für eine Lungeneosinophilie. Es gibt einige Fallberichte über Patienten mit akuter eosinophiler Pneumonie in Verbindung mit Kokainkonsum. Veränderte Gewohnheiten des Hero...
