5 Result(s)
within
Ekkehard Grünig
Internal Medicine
-
Article
Open AccessHereditäre pulmonal-arterielle Hypertonie
Die hereditäre pulmonal-arterielle Hypertonie (PAH) kann durch Mutation in mindestens 18 Genen ausgelöst werden. Das am häufigsten veränderte Gen ist das für den „bone morphogenetic protein receptor 2“ (BMPR2). A...
-
Article
Open AccessOral Treprostinil is Associated with Improved Survival in FREEDOM-EV and its Open-Label Extension
In the event-driven FREEDOM-EV trial, oral treprostinil delayed clinical worsening in patients with pulmonary arterial hypertension (PAH). Open-label extension studies offer additional data about tolerability,...
-
Article
Open AccessDiagnostic accuracy of automated 3D volumetry of cardiac chambers by CT pulmonary angiography for identification of pulmonary hypertension due to left heart disease
To assess diagnostic accuracy of automated 3D volumetry of cardiac chambers based on computed tomography pulmonary angiography (CTPA) for the differentiation of pulmonary hypertension due to left heart disease...
-
Article
Open AccessRiociguat in patients with chronic thromboembolic pulmonary hypertension: results from an early access study
Following positive results from the Phase III CHEST-1 study in patients with inoperable or persistent/recurrent chronic thromboembolic pulmonary hypertension (CTEPH), the Phase IIIb CTEPH early access study (E...
-
Article
Open AccessAcute effects of exercise on the inflammatory state in patients with idiopathic pulmonary arterial hypertension
Exercise training positively influences exercise tolerance and functional capacity of patients with idiopathic pulmonary arterial hypertension (IPAH). However, the underlying mechanisms are unclear. We hypothe...
