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Open AccessDisease control of acromegaly does not prevent excess mortality in the long term: results of a nationwide survey in Italy
This study aimed to assess the long-term outcome of patients with acromegaly.
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Article
Safety and effectiveness of Omnitrope® in patients with growth hormone deficiency: snapshot analysis of PATRO Adults study in the Italian population
PATRO adults is an ongoing, multicenter, observational, post-marketing surveillance study aimed at investigating the long-term safety (primary endpoint) and effectiveness (secondary endpoint) of the recombinan...
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Erratum to: Long-term safety and efficacy of Omnitrope® in adults with growth hormone deficiency: Italian interim analysis of the PATRO Adults study
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Open AccessLong-term safety and efficacy of Omnitrope® in adults with growth hormone deficiency: Italian interim analysis of the PATRO Adults study
To report the long-term effectiveness and safety of the recombinant human growth hormone Omnitrope®, a somatropin biosimilar to Genotropin®, in Italian patients with growth hormone deficiency (GHD) enrolled in th...
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Article
La dissezione profilattica dei linfonodi del comparto centrale nel carcinoma papillare della tiroide: implicazioni cliniche derivate dal primo studio prospettico, randomizzato e controllato, monocentrico
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Article
Regulation of MDM4 (MDMX) function by p76MDM2: a new facet in the control of p53 activity
Under basal growth conditions, p53 function is tightly controlled by the members of MDM family, MDM2 and MDM4. The Mdm2 gene codes, in addition to the full-length p90MDM2, for a short protein, p76MDM2 that lacks ...
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Article
A useful ultrasound score to select thyroid nodules requiring fine needle aspiration in an iodine-deficient area
Background: The high prevalence of thyroid nodules in iodine-deficient areas is a practical problem because of the large number of patients requiring fine needle aspiration (FNA) to detec...
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Article
Fine needle aspiration cytology of thyroid nodules: Conventional vs thin layer technique
Objective: Liquid-based cytology using the thin layer technique has recently been introduced in thyroid fine needle aspiration cytology together with or in substitution of direct smears, ...
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Evaluation of goiter using ultrasound criteria: A survey in a middle schoolchildren population of a mountain area in Central Italy
Iodine deficiency is still an important health care problem in the world. In Italy, as in most European countries, it is responsible for the development of mild to moderate endemic goiter. In 1995 we conducted...
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Article
Biochemical and molecular characterization of the novel BRAFV599Ins mutation detected in a classic papillary thyroid carcinoma
Activating mutations of the BRAF gene are the most common genetic alterations in papillary thyroid carcinomas (PTCs) and the T1799A transversion, resulting in BRAFV600E, appeared virtually unique in this cancer t...
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Article
Cardiovascular response to exercise in diabetic patients: influence of autonomic neuropathy of different severity
We investigated cardiovascular function and plasma catecholamine response during incremental exercise and recovery in diabetic patients with (DAN+) and without autonomic neuropathy (DAN−). The former group was...
