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Article
Open AccessReduced lateralization of multiple functional brain networks in autistic males
Autism spectrum disorder has been linked to a variety of organizational and developmental deviations in the brain. One such organizational difference involves hemispheric lateralization, which may be localized...
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Article
Open AccessGray matter covariations in autism: out-of-sample replication using the ENIGMA autism cohort
Autism spectrum disorder (henceforth autism) is a complex neurodevelopmental condition associated with differences in gray matter (GM) volume covariations, as reported in our previous study of the Longitudinal...
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Article
Open AccessThe neuroanatomical substrates of autism and ADHD and their link to putative genomic underpinnings
Autism spectrum disorders (ASD) are neurodevelopmental conditions accompanied by differences in brain development. Neuroanatomical differences in autism are variable across individuals and likely underpin dist...
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Article
Open AccessDiverging asymmetry of intrinsic functional organization in autism
Autism is a neurodevelopmental condition involving atypical sensory-perceptual functions together with language and socio-cognitive deficits. Previous work has reported subtle alterations in the asymmetry of b...
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Article
Open AccessA stable and replicable neural signature of lifespan adversity in the adult brain
Environmental adversities constitute potent risk factors for psychiatric disorders. Evidence suggests the brain adapts to adversity, possibly in an adversity-type and region-specific manner. However, the long-...
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Article
Open AccessLinking functional and structural brain organisation with behaviour in autism: a multimodal EU-AIMS Longitudinal European Autism Project (LEAP) study
Neuroimaging analyses of brain structure and function in autism have typically been conducted in isolation, missing the sensitivity gains of linking data across modalities. Here we focus on the integration of ...
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Open AccessFine-grained topographic organization within somatosensory cortex during resting-state and emotional face-matching task and its association with ASD traits
Sensory atypicalities are particularly common in autism spectrum disorders (ASD). Nevertheless, our knowledge about the divergent functioning of the underlying somatosensory region and its association with ASD...
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Open AccessCorrection: Understanding the relationship between cerebellar structure and social abilities
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Open AccessUnderstanding the relationship between cerebellar structure and social abilities
The cerebellum contains more than 50% of all neurons in the brain and is involved in a broad range of cognitive functions, including social communication and social cognition. Inconsistent atypicalities in the...
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Article
Open AccessCross-sectional and longitudinal neuroanatomical profiles of distinct clinical (adaptive) outcomes in autism
Individuals with autism spectrum disorder (henceforth referred to as autism) display significant variation in clinical outcome. For instance, across age, some individuals’ adaptive skills naturally improve or ...
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Article
Open AccessPatterns of connectome variability in autism across five functional activation tasks: findings from the LEAP project
Autism spectrum disorder (autism) is a complex neurodevelopmental condition with pronounced behavioral, cognitive, and neural heterogeneities across individuals. Here, our goal was to characterize heterogeneit...
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Open AccessSubtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium
Small average differences in the left-right asymmetry of cerebral cortical thickness have been reported in individuals with autism spectrum disorder (ASD) compared to typically develo** controls, affecting w...
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Open AccessAuthor Correction: Altered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets
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Open AccessModulation of striatal functional connectivity differences in adults with and without autism spectrum disorder in a single-dose randomized trial of cannabidivarin
Autism spectrum disorder (ASD) has a high cost to affected individuals and society, but treatments for core symptoms are lacking. To expand intervention options, it is crucial to gain a better understanding of...
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Article
Open AccessTowards robust and replicable sex differences in the intrinsic brain function of autism
Marked sex differences in autism prevalence accentuate the need to understand the role of biological sex-related factors in autism. Efforts to unravel sex differences in the brain organization of autism have, ...
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Article
Open AccessFractionating autism based on neuroanatomical normative modeling
Autism is a complex neurodevelopmental condition with substantial phenotypic, biological, and etiologic heterogeneity. It remains a challenge to identify biomarkers to stratify autism into replicable cognitive...
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Article
Open AccessGray matter covariations and core symptoms of autism: the EU-AIMS Longitudinal European Autism Project
Voxel-based morphometry (VBM) studies in autism spectrum disorder (autism) have yielded diverging results. This might partly be attributed to structural alterations being associating with the combined influenc...
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Article
Greater cortical thickness in individuals with ASD
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Large-scale analyses of the relationship between sex, age and intelligence quotient heterogeneity and cortical morphometry in autism spectrum disorder
Significant heterogeneity across aetiologies, neurobiology and clinical phenotypes have been observed in individuals with autism spectrum disorder (ASD). Neuroimaging-based neuroanatomical studies of ASD have ...
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Article
Open AccessAltered structural brain asymmetry in autism spectrum disorder in a study of 54 datasets
Altered structural brain asymmetry in autism spectrum disorder (ASD) has been reported. However, findings have been inconsistent, likely due to limited sample sizes. Here we investigated 1,774 individuals with...