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  1. Article

    Open Access

    Subtly altered topological asymmetry of brain structural covariance networks in autism spectrum disorder across 43 datasets from the ENIGMA consortium

    Small average differences in the left-right asymmetry of cerebral cortical thickness have been reported in individuals with autism spectrum disorder (ASD) compared to typically develo** controls, affecting w...

    Zhiqiang Sha, Daan van Rooij, Evdokia Anagnostou, Celso Arango in Molecular Psychiatry (2022)

  2. Article

    Open Access

    Patterns of brain asymmetry associated with polygenic risks for autism and schizophrenia implicate language and executive functions but not brain masculinization

    Autism spectrum disorder (ASD) and schizophrenia have been conceived as partly opposing disorders in terms of systemizing vs. empathizing cognitive styles, with resemblances to male vs. female average sex diff...

    Zhiqiang Sha, Dick Schijven, Clyde Francks in Molecular Psychiatry (2021)

  3. Article

    Open Access

    The genetic architecture of structural left–right asymmetry of the human brain

    Left–right hemispheric asymmetry is an important aspect of healthy brain organization for many functions including language, and it can be altered in cognitive and psychiatric disorders. No mechanism has yet b...

    Zhiqiang Sha, Dick Schijven, Amaia Carrion-Castillo, Marc Joliot in Nature Human Behaviour (2021)

  4. No Access

    Article

    Notch Signaling Activation Promotes Seizure Activity in Temporal Lobe Epilepsy

    Notch signaling in the nervous system is often regarded as a developmental pathway. However, recent studies have suggested that Notch is associated with neuronal discharges. Here, focusing on temporal lobe epi...

    Longze Sha, **aofeng Wu, Yuan Yao, Bo Wen, **g Feng in Molecular Neurobiology (2014)