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  1. Article

    Open Access

    Identification of novel and conserved microRNAs in Panax notoginseng roots by high-throughput sequencing

    MicroRNAs (miRNAs) are small, non-coding RNAs that are important regulators of gene expression, and play major roles in plant development and their response to the environment. Root extracts from Panax notoginsen...

    Rongchang Wei, Deyou Qiu, Iain W. Wilson, Huan Zhao, Shanfa Lu in BMC Genomics (2015)

  2. Article

    Open Access

    De novo transcriptome sequencing and digital gene expression analysis predict biosynthetic pathway of rhynchophylline and isorhynchophylline from Uncaria rhynchophylla, a non-model plant with potent anti-alzheimer’s properties

    The major medicinal alkaloids isolated from Uncaria rhynchophylla (gouteng in chinese) capsules are rhynchophylline (RIN) and isorhynchophylline (IRN). Extracts containing these terpene indole alkaloids (TIAs) ca...

    Qianqian Guo, **aojun Ma, Shugen Wei, Deyou Qiu, Iain W Wilson, Peng Wu in BMC Genomics (2014)

  3. Article

    Open Access

    Genome sequencing and analysis of the paclitaxel-producing endophytic fungus Penicillium aurantiogriseum NRRL 62431

    Paclitaxel (Taxol™) is an important anticancer drug with a unique mode of action. The biosynthesis of paclitaxel had been considered restricted to the Taxus species until it was discovered in Taxomyces andreanae,...

    Yanfang Yang, Hainan Zhao, Roberto A Barrero, Baohong Zhang, Guiling Sun in BMC Genomics (2014)

  4. Article

    Open Access

    De novo assembly of Euphorbia fischeriana root transcriptome identifies prostratin pathway related genes

    Euphorbia fischeriana is an important medicinal plant found in Northeast China. The plant roots contain many medicinal compounds including 12-deoxyphorbol-13-acetate, commonly known as prostratin that is a phorbo...

    Roberto A Barrero, Brett Chapman, Yanfang Yang, Paula Moolhuijzen in BMC Genomics (2011)

  5. Article

    Open Access

    An efficient approach to finding Siraitia grosvenorii triterpene biosynthetic genes by RNA-seq and digital gene expression analysis

    Siraitia grosvenorii (Luohanguo) is an herbaceous perennial plant native to southern China and most prevalent in Guilin city. Its fruit contains a sweet, fleshy, edible pulp that is widely used in traditional Chi...

    Qi Tang, **aojun Ma, Changming Mo, Iain W Wilson, Cai Song, Huan Zhao in BMC Genomics (2011)