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  1. Article

    Open Access

    Correction: A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis

    Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh in Journal of Biomedical Science (2024)

  2. Article

    Open Access

    A novel HIF1α-STIL-FOXM1 axis regulates tumor metastasis

    Metastasis is the major cause of morbidity and mortality in cancer that involves in multiple steps including epithelial–mesenchymal transition (EMT) process. Centrosome is an organelle that functions as the ma...

    Yi-Wei Wang, Shu-Chuan Chen, De-Leung Gu, Yi-Chen Yeh in Journal of Biomedical Science (2022)

  3. No Access

    Article

    PSPC1 mediates TGF-β1 autocrine signalling and Smad2/3 target switching to promote EMT, stemness and metastasis

    Activation of metastatic reprogramming is critical for tumour metastasis. However, more detailed knowledge of the underlying mechanism is needed to enable targeted intervention. Here, we show that paraspeckle ...

    Hsi-Wen Yeh, En-Chi Hsu, Szu-Shuo Lee, Yaw-Dong Lang, Yuh-Charn Lin in Nature Cell Biology (2018)

  4. No Access

    Protocol

    An Introduction to Mitochondrial Informatics

    In this chapter, we review the public resources available for human mitochondrial DNA and protein related bioinformatics, with a special focus on mitochondrial single nucleotide polymorphisms (mtSNPs). We also...

    Hsueh-Wei Chang, Li-Yeh Chuang, Yu-Huei Cheng, De-Leung Gu in Genetic Variation (2010)

  5. Article

    Open Access

    High-throughput avian molecular sexing by SYBR green-based real-time PCR combined with melting curve analysis

    Combination of CHD (chromo-helicase-DNA binding protein)-specific polymerase chain reaction (PCR) with electrophoresis (PCR/electrophoresis) is the most common avian molecular sexing technique but it is lab-inten...

    Hsueh-Wei Chang, Chun-An Cheng, De-Leung Gu, Chia-Che Chang in BMC Biotechnology (2008)

  6. Article

    Open Access

    V-MitoSNP: visualization of human mitochondrial SNPs

    Mitochondrial single nucleotide polymorphisms (mtSNPs) constitute important data when trying to shed some light on human diseases and cancers. Unfortunately, providing relevant mtSNP genoty** information in ...

    Li-Yeh Chuang, Cheng-Hong Yang, Yu-Huei Cheng, De-Leung Gu in BMC Bioinformatics (2006)