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7 Result(s)

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  1. Article

    Open Access

    GPR68 limits the severity of chemical-induced oral epithelial dysplasia

    Head and neck cancer is the sixth most common malignancy, and there is an urgent need to identify physiological processes contributing to tumorigenesis. Extracellular acidification caused by aerobic glycolysis...

    David Shore, Nosakhere Griggs, Vincent Graffeo, A. R. M. Ruhul Amin… in Scientific Reports (2023)

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  2. Article

    Open Access

    Pitfalls in using phenanthroline to study the causal relationship between promoter nucleosome acetylation and transcription

    Sevil Zencir, Daniel Dilg, David Shore, Benjamin Albert in Nature Communications (2022)

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  3. Article

    Open Access

    Rif1 S-acylation mediates DNA double-strand break repair at the inner nuclear membrane

    Rif1 is involved in telomere homeostasis, DNA replication timing, and DNA double-strand break (DSB) repair pathway choice from yeast to human. The molecular mechanisms that enable Rif1 to fulfill its diverse r...

    Gabriele A. Fontana, Daniel Hess, Julia K. Reinert… in Nature Communications (2019)

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  4. Article

    Open Access

    A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus

    Effective annual influenza vaccination requires frequent changes in vaccine composition due to both antigenic shift for different subtype hemagglutinins (HAs) and antigenic drift in a particular HA. Here we pr...

    Ying Wu, MyungSam Cho, David Shore, Manki Song, JungAh Choi… in Nature Communications (2015)

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  5. No Access

    Article

    Growth-regulated recruitment of the essential yeast ribosomal protein gene activator Ifh1

    Regulation of ribosome biogenesis is central to the control of cell growth1. In rapidly growing yeast cells, ribosomal protein (RP) genes account for approximately one-half of all polymerase II transcription-init...

    Stephan B. Schawalder, Mehdi Kabani, Isabelle Howald, Urmila Choudhury… in Nature (2004)

  6. No Access

    Article

    Chromosomal landscape of nucleosome-dependent gene expression and silencing in yeast

    Eukaryotic genomes are packaged into nucleosomes, which are thought to repress gene expression generally1,2,3. Repression is particularly evident at yeast telomeres, where genes within the telomeric heterochromat...

    John J. Wyrick, Frank C. P. Holstege, Ezra G. Jennings, Helen C. Causton… in Nature (1999)

  7. No Access

    Article

    Different means to common ends

    David Shore in Nature (1997)