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    Article

    Pharmaceutical and Immunological Evaluation of Cholera Toxin A1 Subunit as an Adjuvant of Hepatitis B Vaccine Microneedles

    For successful delivery of a solid vaccine formulation into the skin using microneedles, the solubility of an adjuvant should be considered because the decrease in the dissolution rate by the addition of adjuv...

    Jong-Chan Kim, Jung-ah Choi, Hayan Park, Eunji Yang in Pharmaceutical Research (2023)

  2. Article

    Open Access

    Heterologous vaccination utilizing viral vector and protein platforms confers complete protection against SFTSV

    Severe fever with thrombocytopenia syndrome virus was first discovered in 2009 as the causative agent of severe fever with thrombocytopenia syndrome. Despite its potential threat to public health, no prophylac...

    Jae-Yong Kim, Kyeongseok Jeon, Jung Joo Hong, Sang-In Park in Scientific Reports (2023)

  3. Article

    Open Access

    Interim analysis from a phase 2 randomized trial of EuCorVac-19: a recombinant protein SARS-CoV-2 RBD nanoliposome vaccine

    Numerous vaccine strategies are being advanced to control SARS-CoV-2, the cause of the COVID-19 pandemic. EuCorVac-19 (ECV19) is a recombinant protein nanoparticle vaccine that displays the SARS-CoV-2 receptor...

    Jonathan F. Lovell, Yeong Ok Baik, Seuk Keun Choi, Chankyu Lee in BMC Medicine (2022)

  4. Article

    Open Access

    Laboratory information management system for COVID-19 non-clinical efficacy trial data

    As the number of large-scale studies involving multiple organizations producing data has steadily increased, an integrated system for a common interoperable format is needed. In response to the coronavirus dis...

    Suhyeon Yoon, Hyuna Noh, Hee** **, Sungyoung Lee, Soyul Han in Laboratory Animal Research (2022)

  5. Article

    Open Access

    A potent broad-spectrum protective human monoclonal antibody crosslinking two haemagglutinin monomers of influenza A virus

    Effective annual influenza vaccination requires frequent changes in vaccine composition due to both antigenic shift for different subtype hemagglutinins (HAs) and antigenic drift in a particular HA. Here we pr...

    Ying Wu, MyungSam Cho, David Shore, Manki Song, JungAh Choi in Nature Communications (2015)

  6. Article

    Preliminary study about sublingual administration of bacteria-expressed pandemic H1N1 influenza vaccine in miniature pigs

    Sublingual (SL) administration of influenza vaccine would be non-invasive and effective way to give human populations protective immunity against the virus, especially when pandemic influenza outbreaks. In thi...

    Hyekwon Kim, Jeong-Ki Kim, Hohyun Song, Jungah Choi in Journal of Microbiology (2014)