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Article
Tumor-Derived Membrane Vesicles from the IL-2 Overexpression Melanoma Cells Affect on the Expression of Surface Markers of Human Peripheral Blood Mononuclear Cells In Vitro
Nowadays, immunotherapy, in particular immunotherapeutic vaccines, is a promising approach in the treatment of cancer which has already demonstrated its effectiveness. Extracellular vesicles (EVs), which are c...
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Article
In Vivo Visualization of Stable Neuroblastoma Cell Lines with Overexpression of Firefly Luciferase or Far-Red Fluorescent Protein
The development of imaging techniques in the experimental oncology has made it possible to model and continuously monitor growth and development of tumors in vivo. For this purpose, fluorescent or bioluminesce...
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Article
Analysis of the Interaction of Human Neuroblastoma Cell-Derived Cytochalasin B Induced Membrane Vesicles with Mesenchymal Stem Cells Using Imaging Flow Cytometry
At present, there is an increasing interest in the potential role of extracellular vesicles (EVs), acting as multi-signal messengers of the tumor stroma, in the development and progression of tumor. Tumor cell...
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Article
Recombinant histone H1.3 inhibits orthohantavirus infection in vitro
Histones are proteins participating in DNA packaging. Despite this limited function, histones were shown to have antiviral activity. Histone H1.3 has been shown to inhibit adenovirus infection. Orthohantavirus...
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Article
In Vitro Angiogenic Properties of Plasmid DNA Encoding SDF-1α and VEGF165 Genes
The stromal-derived factor-1 alpha (SDF-1α) and vascular endothelial growth factor (VEGF) play an important role in angiogenesis and exert a significant trophic function. SDF-1α is a chemoattractant for endoth...
