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Article
Open AccessVegetation structure drives mosquito community composition in UK’s largest managed lowland wetland
The rising burden of mosquito-borne diseases in Europe extends beyond urban areas, encompassing rural and semi-urban regions near managed and natural wetlands evidenced by recent outbreaks of Usutu and West Ni...
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Article
Open AccessTREM2 splice isoforms generate soluble TREM2 species that disrupt long-term potentiation
TREM2 is a transmembrane receptor expressed by myeloid cells and acts to regulate their immune response. TREM2 governs the response of microglia to amyloid and tau pathologies in the Alzheimer’s disease (AD) b...
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Chapter and Conference Paper
DART – Providing Distress Assistance with Real-Time Aircraft Telemetry
ICAO has long recognized the need to transmit data off an aircraft while still in flight, especially in remote areas. To locate an aircraft in distress more quickly, and to allow investigators more timely acce...
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Article
Open AccessTuning recombinant protein expression to match secretion capacity
The secretion of recombinant disulfide-bond containing proteins into the periplasm of Gram-negative bacterial hosts, such as E. coli, has many advantages that can facilitate product isolation, quality and activit...
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Article
Open AccessDevelopment of a generic β-lactamase screening system for improved signal peptides for periplasmic targeting of recombinant proteins in Escherichia coli
Targeting of recombinant proteins to the Escherichia coli periplasm is a desirable industrial processing tool to allow formation of disulphide bonds, aid folding and simplify recovery. Proteins are targeted acros...
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Article
Unjustified prices: environmental drivers of managers’ propensity to overprice
Ideally, a product’s price should strike a balance between extracting value for a firm and sharing some of that value with customers. Charging less than what is warranted by a product’s value “leaves money on ...
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Article
Open AccessRetrograde transport pathways utilised by viruses and protein toxins
A model has been presented for retrograde transport of certain toxins and viruses from the cell surface to the ER that suggests an obligatory interaction with a glycolipid receptor at the cell surface. Here we...
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Article
Brand-extension price premiums: The effects of perceived fit and extension product category risk
One of the assumed benefits of extending a strong brand into a new product category is the ability to capture a price premium relative to comparable products associated with lower equity brands. The authors ar...
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Article
The importance and challenges of being interesting
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Article
Ricin
Ricin is a heterodimeric protein produced in the seeds of the castor oil plant (Ricinus communis). It is exquisitely potent to mammalian cells, being able to fatally disrupt protein synthesis by attacking the Ach...
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Article
Expression, purification and characterization of ricin vectors used for exogenous antigen delivery into the MHC class I presentation pathway
Disarmed versions of the cytotoxin ricin can deliver fused peptides into target cells leading to MHC class I-restricted antigen presentation [Smithet al. J Immunol 2002; 169:99–107]. The ricin delivery vector mus...
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Chapter
Einfluß der Markenerweiterung auf Marktanteil und Werbeeffizienz
Eine der wertvollsten Ressourcen eines Unternehmens ist seine historische Marktpräsenz. Der Glaube des Konsumenten an die Marke und sein Eindruck von der Marke gehören zu den Hauptquellen dieser Ressource. Bei...
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Chapter
Einfluß des Produktportfolios auf die Markenstärke
Zu den wertvollsten Ressourcen eines Unternehmens gehört der Ruf seiner Marken. Um diesen Wert zu vergrößern, dehnen immer mehr Unternehmen ihre Marken auf eine Vielzahl von Produktkategorien aus. Als Resultat...
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Chapter
Einfluß der Markenerweiterung auf Marktanteil und Werbeeffizienz
Eine der wertvollsten Ressourcen eines Unternehmens ist seine historische Marktpräsenz. Der Glaube des Konsumenten an die Marke und sein Eindruck von der Marke gehören zu den Hauptquellen dieser Ressource. Bei...
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Chapter
Einfluß des Produktportfolios auf die Markenstärke
Zu den wertvollsten Ressourcen eines Unternehmens gehört der Ruf seiner Marken. Um diesen Wert zu vergrößern, dehnen immer mehr Unternehmen ihre Marken auf eine Vielzahl von Produktkategorien aus. Als Resultat...
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Chapter
Einfluß des Produktportfolios auf die Markenstärke
Zu den wertvollsten Ressourcen eines Unternehmens gehört der Ruf seiner Marken. Um diesen Wert zu vergrößern, dehnen immer mehr Unternehmen ihre Marken auf eine Vielzahl von Produktkategorien aus. Als Resultat...
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Chapter
Einfluß der Markenerweiterung auf Marktanteil und Werbeeffizienz
Eine der wertvollsten Ressourcen eines Unternehmens ist seine historische Marktpräsenz. Der Glaube des Konsumenten an die Marke und sein Eindruck von der Marke gehören zu den Hauptquellen dieser Ressource. Bei...
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Article
How does sharing a sales force between multiple divisions affect salespeople?
An increasing number of firms are sharing a sales force between multiple divisions of their companies. Although this practice may increase organizational efficiency by reducing unit selling costs, it is not cl...
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Article
Rethinking the effect of perceived fit on customers’ evaluations of new products
Prior research has demonstrated that customer evaluations of a new product are directly related to the degree to which a company’s skills are perceived to “fit” with those required to provide the new product. ...
