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Article
Pharmacokinetic study of3H-labelled PAF-acether II. Comparison with3H-labelled lyso-PAF-acether after intravenous administration in the rabbit and protein binding
The blood and plasma kinetics of intravenously administered3H-labelled PAF-acether were determined in seven rabbits. PAF-acether was rapidly distributed and slowly eliminated. Individual variations were very smal...
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Article
Comparative physico-chemical properties, biological effects, and disposition in mice of four nitrogen mustards
Chlorambucil, phenyl acetic mustard, melphalan and mitoclomine are aromatic nitrogen mustard derivatives. These drugs show a fairly wide range of chemical reactivity and lipophilicity. In the series presently ...