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    Article

    Comparative study of the biotransformation of bepridil analogs in isolated liver cells from one rat. Relationships between structure and in vitro liver toxicity

    The biotransformation of several analogs of the anti-calcium agent bepridil was studied comparatively in liver cells isolated from one rat. Three types of metabolites were identified by mass spectrometry, resu...

    E. Damatte, M. J. Galmier… in European Journal of Drug Metabolism and Ph… (1996)

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    Article

    Pharmacokinetic study of3H-labelled PAF-acether II. Comparison with3H-labelled lyso-PAF-acether after intravenous administration in the rabbit and protein binding

    The blood and plasma kinetics of intravenously administered3H-labelled PAF-acether were determined in seven rabbits. PAF-acether was rapidly distributed and slowly eliminated. Individual variations were very smal...

    C. Lartigue-Mattei, D. Godeneche, J. L. Chabard, J. Petit… in Agents and Actions (1984)