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Article
Open AccessReal world data on outcomes of anti-CD38 antibody treated, including triple class refractory, patients with multiple myeloma: a multi-institutional report from the Canadian Myeloma Research Group (CMRG) Database
Multiple myeloma (MM) remains incurable despite the availability of novel agents. This multi-center retrospective cohort study used the Canadian Myeloma Research Group Database to describe real-world outcomes ...
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Article
Relationship between Social Support, Sarcopenia, and Cognitive Impairment in Chinese Community-Dwelling Older Adults
Cognitive impairment and sarcopenia have become important challenges for the growing aging population. Social support has been shown to protect against cognitive impairment, but its impact on sarcopenia remain...
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Article
Correction to: Smad7 is inactivated through a direct physical interaction with the LIM protein Hic-5/ARA55
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Article
Open AccessControlling spin current polarization through non-collinear antiferromagnetism
The interconversion of charge and spin currents via spin-Hall effect is essential for spintronics. Energy-efficient and deterministic switching of magnetization can be achieved when spin polarizations of these...
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Article
Design of a neutral elastic inhomogeneity via thermal expansion
A neutral elastic inhomogeneity does not affect the existing stress field when inserted into an elastic body. It has been shown that no such inhomogeneity can exist under the classical assumption of a perfectl...
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Article
Effective conductivity and the effect of electric current on thermal stress around an arbitrarily shaped inhomogeneity
We consider the electric, thermal and elastic fields in an infinite conductor or semiconductor plate containing an arbitrarily shaped inhomogeneity. Complex variable and numerical methods are used to discuss e...
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Article
Serum Stem Cell Factor Level Predicts Decline in Kidney Function in Healthy Aging Adults
Stem cell factor (SCF), the ligand of the c-kit receptor, actively participates in the organ reconstruction and fibrosis associated with various diseases, including kidney disease. However, it remains unclear ...
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Article
Open AccessEfficacy and safety of carfilzomib regimens in multiple myeloma patients relapsing after autologous stem cell transplant: ASPIRE and ENDEAVOR outcomes
Autologous stem cell transplantation (ASCT) is a standard treatment for eligible multiple myeloma (MM) patients, but many patients will relapse after ASCT and require subsequent therapy. The proteasome inhibit...
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Article
An Atom Probe Study of κ-carbide Precipitation in Austenitic Lightweight Steel and the Effect of Phosphorus
The influence of phosphorus on κ-carbide precipitation and alloy partitioning in an austenitic Fe-30Mn-9Al-1Si-0.9C-0.5Mo cast steel was studied utilizing a combination of transmission electron microscopy, 3D ...
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Article
Open AccessSkin renewal activity of non-thermal plasma through the activation of β-catenin in keratinocytes
For recent years, devices that generate non-thermal plasma (NTP) have been introduced into the field of dermatology. Since NTP has demonstrated strong anti-pathogenic activity with safety of use, NTP was first...
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Article
Serum uric acid is an independent predictor for develo** prehypertension: a population-based prospective cohort study
Although the prevalence of prehypertension is rapidly increasing in China, the medical community has paid little attention to its prevention. Prior studies have demonstrated that uric acid directly contributes...
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Article
Consumption of chilies, but not sweet peppers, is positively related to handgrip strength in an adult population
Chili consumption may have a beneficial effect on muscle strength in the general population. The aim of this study was to investigate the relationship between frequency of chili consumption and handgrip streng...
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Article
Effect of Mg2Sn Intermetallic on the Grain Refinement in As-cast AM Series Alloy
In the present work, in order to investigate the grain refinement mechanism of AM containing Sn alloys, the as-cast AM60, AM90 alloys, and the alloys with addition of 1 wt.% Sn were fabricated by traditional c...
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Article
Dietary patterns are associated with prevalence of fatty liver disease in adults
Previous studies have indicated that higher levels of food consumption are associated with fatty liver disease (FLD), but few studies have investigated the relationship between this disease and different dieta...
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Article
Erratum: Effects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects
Correction to: Molecular Psychiatry (2013) 18; 1287–1293; doi:10.1038/mp.2012.154 Following publication, the authors noticed that the bottom three panels of Figure 2 were incorrect. The correct version of Figu...
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Article
Open AccessTreatment outcomes in patients with relapsed and refractory multiple myeloma and high-risk cytogenetics receiving single-agent carfilzomib in the PX-171-003-A1 study
Several cytogenetic abnormalities are associated with poor outcomes in multiple myeloma (MM). We prospectively analyzed the impact of cytogenetic abnormalities on outcomes during the phase 2 PX-171-003-A1 stud...
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Article
Open AccessEffects of the mu-opioid receptor antagonist GSK1521498 on hedonic and consummatory eating behaviour: a proof of mechanism study in binge-eating obese subjects
The opioid system is implicated in the hedonic and motivational processing of food, and in binge eating, a behaviour strongly linked to obesity. The aim of this study was to evaluate the effects of 4 weeks of ...
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Article
Distribution characteristics of fission gas along the axial direction for an irradiated fuel rod of a pressurized water reactor (PWR)
In this work, the fission gas distribution of an irradiated oxide fuel was investigated by measuring the fission gas release (FGR) and retained gas from and in an oxide fuel along the axial height of the fuel ...
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Article
Open AccesskillerFLIP: a novel lytic peptide specifically inducing cancer cell death
One of the objectives in the development of effective cancer therapy is induction of tumor-selective cell death. Toward this end, we have identified a small peptide that, when introduced into cells via a TAT c...
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Article
Pseudo-autologous hematopoietic SCT as treatment for a patient with multiple myeloma who relapsed following an allogeneic hematopoietic SCT
