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Mitochondrial Mutations and the Ageing Process
We have proposed that the accumulation of random somatic gene mutations in the mitochondrial DNA (mtDNA) during life is an important contributor to the ageing process. The consequence of these mutations is the...
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Article
Supercondcuting properties in MgB2/Fe wires prepared by PIT method
The MgB2 formation was analyzed physically and chemically and the MgB2/Fe wires were fabricated by powder in tube (PIT) technology. The microstructure of MgB2 in wires was studied by the scanning electrical micro...
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Article
Detection of coalbed fractures with P-wave azimuthal AVO in 3-D seismic exploration
The detection of fractures is important for production and safety in coal fields. Subsurface fractures result in azimuthal anisotropy of the seismic wave, and the amplitude of reflection wave varies with offse...
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Article
Filamentous cyanobacteria fossils and their significance in the Permian-Triassic boundary section at Laolongdong, Chongqing
The microbial communities blooming immediately after the end-Permian mass extinction represent abnormally extreme environments, and vary in different areas. In this study, filamentous cyanobacterial biota was ...
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Open AccessGenome sequencing reveals insights into physiology and longevity of the naked mole rat
The mouse-sized naked mole rat (Heterocephalus glaber) is a very unusual mammal. It is a social animal, living in groups in burrows beneath arid African deserts. It can live for 30 or more years in atmospheres wi...
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Open AccessLipids of sulfate-reducing bacteria and sulfur-oxidizing bacteria found in the Dongsheng uranium deposit
U-bearing sandstones from the Dongsheng deposit in Ordos Basin contain abundant C15-C18 fatty acids. The fatty acids may have been derived from modern and ancient organisms including organisms from the intervals ...
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Article
Open AccessGenome sequence of the model medicinal mushroom Ganoderma lucidum
Ganoderma lucidum is a widely used medicinal macrofungus in traditional Chinese medicine that creates a diverse set of bioactive compounds. Here we report its 43.3-Mb genome, encoding 16,113 predicted genes, obta...
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Open AccessThe oyster genome reveals stress adaptation and complexity of shell formation
The Pacific oyster Crassostrea gigas belongs to one of the most species-rich but genomically poorly explored phyla, the Mollusca. Here we report the sequencing and assembly of the oyster genome using short reads ...
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Open AccessSpontaneous generation of germline characteristics in mouse fibrosarcoma cells
Germline/embryonic-specific genes have been found to be activated in somatic tumors. In this study, we further showed that cells functioning as germline could be present in mouse fibrosarcoma cells (L929 cell ...
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Open AccessS100+ cells: A new neuro-immune cross-talkers in lymph organs
Up to now, the ‘hardwired’ neural pathway of the neuro-immune regulation is not fully understood. Here we reported a new neural pathway which links sympathetic nerves with immune cells of the lymphoid tissues....
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Article
Open AccessActivation of the germ-cell potential of human bone marrow-derived cells by a chemical carcinogen
Embryonic/germ cell traits are common in malignant tumors and are thought to be involved in malignant tumor behaviors. The reasons why tumors show strong embryonic/germline traits (displaced germ cells or game...
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Article
Redox condition during Ediacaran–Cambrian transition in the Lower Yangtze deep water basin, South China: constraints from iron speciation and δ 13Corg in the Diben section, Zhejiang
Cherts of the Piyuancun Formation and black mudstones of the Hetang Formation in Diben Town, Kaihua County, Zhejiang were deposited in a deep water basin of the Lower Yangtze area during the Ediacaran–Cambrian...
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Open AccessEvolutionary analysis of rubella viruses in mainland China during 2010–2012: endemic circulation of genotype 1E and introductions of genotype 2B
Rubella remains a significant burden in mainland China. In this report, 667 viruses collected in 24 of 31 provinces of mainland China during 2010–2012 were sequenced and analyzed, significantly extending previ...
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Open AccessUncovering pharmacological mechanisms of Wu-tou decoction acting on rheumatoid arthritis through systems approaches: drug-target prediction, network analysis and experimental validation
Wu-tou decoction (WTD) has been extensively used for the treatment of rheumatoid arthritis (RA). Due to lack of appropriate methods, pharmacological mechanisms of WTD acting on RA have not been fully elucidate...
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Article
Open AccessSingle fluoxetine treatment before but not after stress prevents stress-induced hippocampal long-term depression and spatial memory retrieval impairment in rats
A growing body of evidence has shown that chronic treatment with fluoxetine, a widely prescribed medication for treatment of depression, can affect synaptic plasticity in the adult central nervous system. Howe...
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Deletion of a DnaK protein gene causes seedling green-revertible albino by retarding chloroplast development in rice
Green-revertible albino mutants are important sources for studying chloroplast structure, chloroplast development, chlorophyll biosynthesis, and plant photosynthesis. In the present study, we characterized a g...
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Open AccessBlood lead level and its association with body mass index and obesity in China - Results from SPECT-China study
We aimed to report environmental and blood lead level (BLL) in China and investigate the relationship of BLL with body mass index (BMI) and obesity. 5558 subjects were enrolled from 16 sites in China. BLL was ...
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Article
Open AccessSpatial Abundance and Distribution of Potential Microbes and Functional Genes Associated with Anaerobic Mineralization of Pentachlorophenol in a Cylindrical Reactor
Functional interplays of microbial activity, genetic diversity and contaminant transformation are poorly understood in reactors for mineralizing halogenated aromatics anaerobically. Here, we investigated abund...
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Article
Open AccessNon-adiabatic holonomic quantum computation in linear system-bath coupling
Non-adiabatic holonomic quantum computation in decoherence-free subspaces protects quantum information from control imprecisions and decoherence. For the non-collective decoherence that each qubit has its own ...
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Article
Open AccessPrevalence of colonic diverticulosis in mainland China from 2004 to 2014
The aim of this study was to determine the prevalence of colonic diverticulosis in mainland China. Sixty two thousand and thirty-four colonoscopies performed between Jan 2004 and Dec 2014 were reviewed retrosp...