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Article
Position-dependent termination and widespread obligatory frameshifting in Euplotes translation
Large-scale sequencing approaches reveal that the genetic code of Euplotes ciliates supports widespread ribosomal frameshifting at stop codons, and that additional mechanisms are required for efficient translatio...
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Article
Open AccessAnalysis of cancer genomes reveals basic features of human aging and its role in cancer development
Somatic mutations have long been implicated in aging and disease, but their impact on fitness and function is difficult to assess. Here by analysing human cancer genomes we identify mutational patterns associa...
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The Naked Mole Rat and Selenium
The naked mole rat, Heterocephalus glaber, has emerged as a popular model organism for studying aging, hypoxia tolerance and cancer resistance. The sequencing of its genome and transcriptome allowed researchers t...
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Article
Open AccessGenome sequencing reveals insights into physiology and longevity of the naked mole rat
The mouse-sized naked mole rat (Heterocephalus glaber) is a very unusual mammal. It is a social animal, living in groups in burrows beneath arid African deserts. It can live for 30 or more years in atmospheres wi...
