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Elevated serum levels of interleukin-18 are associated with insulin resistance in women with polycystic ovary syndrome

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  1. Article

    Open Access

    A vacuole localized β-glucosidase contributes to drought tolerance in Arabidopsis

    The phytohormone abscisic acid (ABA) plays a critical role in plant growth, development, and adaptation to various stress conditions. The cellular ABA level is constantly adjusted to respond to changing physio...

    PengTao Wang, Hao Liu, HongJie Hua, Lei Wang, Chun-Peng Song in Chinese Science Bulletin (2011)

  2. Article

    Open Access

    Efficient and tunable white-light emission of metal–organic frameworks by iridium-complex encapsulation

    Metal–organic frameworks (MOFs) are well known for their tunable structure and porosity. Many studies have shown they are promising for various important applications, for which their performance can be furthe...

    Chun-Yi Sun, **n-Long Wang, **ao Zhang, Chao Qin, Peng Li in Nature Communications (2013)

  3. Article

    Open Access

    Real-Time Light Scattering Tracking of Gold Nanoparticles- bioconjugated Respiratory Syncytial Virus Infecting HEp-2 Cells

    Real-time tracking of virus invasion is crucial for understanding viral infection mechanism, which, however, needs simple and efficient labeling chemistry with improved signal-to-noise ratio. For that purpose,...

    **ao-Yan Wan, Lin-Ling Zheng, Peng-Fei Gao, **ao-** Yang, Chun-Mei Li in Scientific Reports (2014)

  4. Article

    Open Access

    Label-free detection of kanamycin based on a G-quadruplex DNA aptamer-based fluorescent intercalator displacement assay

    This work was the first to report that the kanamycin-binding DNA aptamer (5′-TGG GGG TTG AGG CTA AGC CGA-3′) can form stable parallel G-quadruplex DNA (G4-DNA) structures by themselves and that this phenomenon...

    Yun-Peng **ng, Chun Liu, **ao-Hong Zhou, Han-Chang Shi in Scientific Reports (2015)

  5. Article

    Open Access

    Ancient inland human dispersals from Myanmar into interior East Asia since the Late Pleistocene

    Given the existence of plenty of river valleys connecting Southeast and East Asia, it is possible that some inland route(s) might have been adopted by the initial settlers to migrate into the interior of East ...

    Yu-Chun Li, Hua-Wei Wang, Jiao-Yang Tian, Li-Na Liu, Li-Qin Yang in Scientific Reports (2015)

  6. Article

    Open Access

    Ubiquitin-protein ligase E3C promotes glioma progression by mediating the ubiquitination and degrading of Annexin A7

    The ubiquitin-protein ligase E3C (UBE3C) belongs to the E3 ligase enzyme family and implicates in the ubiquitin-proteasome pathway, thus regulates physiological and cancer-related processes. Here, we investiga...

    Si-Jian Pan, Shi-Kun Zhan, Wei-Zhong Ji, Yi-**n Pan, Wei Liu in Scientific Reports (2015)

  7. Article

    Open Access

    Generation of inheritable and “transgene clean” targeted genome-modified rice in later generations using the CRISPR/Cas9 system

    The CRISPR/Cas9 system is becoming an important genome editing tool for crop breeding. Although it has been demonstrated that target mutations can be transmitted to the next generation, their inheritance patte...

    Rong-Fang Xu, Hao Li, Rui-Ying Qin, Juan Li, Chun-Hong Qiu in Scientific Reports (2015)

  8. Article

    Open Access

    Structural, energetic and dynamic insights into the abnormal xylene separation behavior of hierarchical porous crystal

    Separation of highly similar molecules and understanding the underlying mechanism are of paramount theoretical and practical importance, but visualization of the host-guest structure, energy, or dynamism is ve...

    Jiao-Min Lin, Chun-Ting He, Pei-Qin Liao, Rui-Biao Lin in Scientific Reports (2015)

  9. Article

    Open Access

    A systematic analysis of human lipocalin family and its expression in esophageal carcinoma

    The lipocalin proteins (lipocalins) are a large family of small proteins characterized by low sequence similarity and highly conserved crystal structures. Lipocalins have been found to play important roles in ...

    Ze-Peng Du, Bing-Li Wu, Xuan Wu, Xuan-Hao Lin, **ao-Yang Qiu in Scientific Reports (2015)

  10. Article

    Open Access

    Large-scale genomics unveil polygenic architecture of human cortical surface area

    Little is known about how genetic variation contributes to neuroanatomical variability, and whether particular genomic regions comprising genes or evolutionarily conserved elements are enriched for effects tha...

    Chi-Hua Chen, Qian Peng, Andrew J. Schork, Min-Tzu Lo in Nature Communications (2015)

  11. Article

    Open Access

    miRNA-133 augments coelomocyte phagocytosis in bacteria-challenged Apostichopus japonicus via targeting the TLR component of IRAK-1 in vitro and in vivo

    In this study, we explored the potential roles of miRNA-133 in regulating TLR pathways in the sea cucumber Apostichopus japonicus. Target screening of RNA-Seq data successfully identified interleukin-1 receptor-a...

    Meng Lu, Peng-Juan Zhang, Cheng-Hua Li, Zhi-Meng Lv, Wei-Wei Zhang in Scientific Reports (2015)

  12. Article

    Open Access

    Accommodating lithium into 3D current collectors with a submicron skeleton towards long-life lithium metal anodes

    Lithium metal is one of the most attractive anode materials for electrochemical energy storage. However, the growth of Li dendrites during electrochemical deposition, which leads to a low Coulombic efficiency ...

    Chun-Peng Yang, Ya-**a Yin, Shuai-Feng Zhang, Nian-Wu Li in Nature Communications (2015)

  13. Article

    Open Access

    Dissolution-and-reduction CVD synthesis of few-layer graphene on ultra-thin nickel film lifted off for mode-locking fiber lasers

    The in-situ dissolution-and-reduction CVD synthesized few-layer graphene on ultra-thin nickel catalyst film is demonstrated at temperature as low as 550 °C, which can be employed to form transmission-type or refl...

    Kaung-Jay Peng, Yung-Hsiang Lin, Chung-Lun Wu, Sheng-Fong Lin in Scientific Reports (2015)

  14. Article

    Open Access

    Modeling the interplay between the HIF-1 and p53 pathways in hypoxia

    Both the hypoxia-inducible factor-1 (HIF-1) and tumor suppressor p53 are involved in the cellular response to hypoxia. How the two transcription factors interact to determine cell fates is less well understood...

    Chun-Hong Zhou, **ao-Peng Zhang, Feng Liu, Wei Wang in Scientific Reports (2015)

  15. Article

    Open Access

    Interaction between microRNA expression and classical risk factors in the risk of coronary heart disease

    The aim of this study was to identify the synergistic effect of microRNA expression with classical risk factors of coronary heart disease (CHD) and to explore their diagnostic value for coronary stenotic lesio...

    **ao-Qing Ding, Peng-Cheng Ge, Zhe Liu, Heng Jia, ** Chen in Scientific Reports (2015)

  16. Article

    Open Access

    Ancient Chinese Formula Qiong-Yu-Gao Protects Against Cisplatin-Induced Nephrotoxicity Without Reducing Anti-tumor Activity

    Cisplatin is a highly effective anti-cancer chemotherapeutic agent; however, its clinical use is severely limited by serious side effects, of which nephrotoxicity is the most important. In this study, we inves...

    Zhi-Ying Teng, **ao-Lan Cheng, Xue-Ting Cai, Yang Yang, **ao-Yan Sun in Scientific Reports (2015)

  17. Article

    Open Access

    Screening and Molecular Analysis of Single Circulating Tumor Cells Using Micromagnet Array

    Immunomagnetic assay has been developed to detect rare circulating tumor cells (CTCs), which shows clinical significance in cancer diagnosis and prognosis. The generation and fine-tuning of the magnetic field ...

    Yu-Yen Huang, Peng Chen, Chun-Hsien Wu, Kazunori Hoshino in Scientific Reports (2015)

  18. Article

    Open Access

    Hemicelluloses/montmorillonite hybrid films with improved mechanical and barrier properties

    A facile and environmentally friendly method was introduced to incorporate montmorillonite (MMT) as an inorganic phase into quaternized hemicelluloses (QH) for forming hemicellulose-based films. Two fillers, p...

    Ge-Gu Chen, **an-Ming Qi, Ming-Peng Li, Ying Guan, **g Bian in Scientific Reports (2015)

  19. Article

    Open Access

    Treating Colon Cancer Cells with FK228 Reveals a Link between Histone Lysine Acetylation and Extensive Changes in the Cellular Proteome

    The therapeutic value of FK228 as a cancer treatment option is well known and various types of cancer have been shown to respond to this drug. However, the complete mechanism of FK228 and the affect it has on ...

    Tian-yun Wang, Yan-long Jia, ** Zhang, Qiu-li Sun, Yi-Chun Li in Scientific Reports (2015)

  20. Article

    Open Access

    The Roles of MicroRNA-122 Overexpression in Inhibiting Proliferation and Invasion and Stimulating Apoptosis of Human Cholangiocarcinoma Cells

    Our study investigated whether microRNA-122 (miR-122) played important roles in the proliferation, invasion and apoptosis of human cholangiocarcinoma (CC) cells. QBC939 and RBE cells lines were chosen and divi...

    Ning Liu, Fan Jiang, Tian-Lin He, Jun-Kuan Zhang, Juan Zhao in Scientific Reports (2015)

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