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Open AccessReduction of inappropriate medication in older populations by electronic decision support (the PRIMA-eDS study): a qualitative study of practical implementation in primary care
Within the EU-funded project PRIMA-eDS (Polypharmacy in chronic diseases: Reduction of Inappropriate Medication and Adverse drug events in older populations by electronic Decision Support) an electronic decision ...
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Article
Open AccessCorrection to: Effectiveness and safety of vitamin K antagonists and new anticoagulants in the prevention of thromboembolism in atrial fibrillation in older adults – a systematic review of reviews and the development of recommendations to reduce inappropriate prescribing
After publication of the original article [1] it was found that author Marc Krause’s name had been spelt incorrectly.
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Article
Open AccessEfficacy and safety of metformin in the management of type 2 diabetes mellitus in older adults: a systematic review for the development of recommendations to reduce potentially inappropriate prescribing
Metformin is usually prescribed as first line therapy for type 2 diabetes mellitus (DM2). However, the benefits and risks of metformin may be different for older people. This systematic review examined the ava...
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Article
Open AccessEffectiveness and patient safety of platelet aggregation inhibitors in the prevention of cardiovascular disease and ischemic stroke in older adults – a systematic review
Platelet aggregation inhibitors (PAI) are among the most frequently prescribed drugs in older people, though evidence about risks and benefits of their use in older adults is scarce. The objectives of this sys...
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Open AccessA set of systematic reviews to help reduce inappropriate prescribing to older people: study protocol
Multimorbidity and polypharmacy are common in older people. Assessment tools or lists of criteria aimed at supporting prescription decisions for older people exist, but have often been based on expert opinion ...
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Article
Open AccessEffectiveness and safety of vitamin K antagonists and new anticoagulants in the prevention of thromboembolism in atrial fibrillation in older adults – a systematic review of reviews and the development of recommendations to reduce inappropriate prescribing
Oral anticoagulants are used for stroke prevention in patients with atrial fibrillation, the most common cardiac arrhythmia in older adults. The aim of our study was to identify the evidence on the risks and b...
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Article
Open AccessThiazides in the management of hypertension in older adults – a systematic review
Thiazides are commonly prescribed to older people for the management of hypertension. The objective of this study was to identify the evidence on the risks and benefits of their use among adults aged ≥65 years...
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Article
Chlortalidon versus Hydrochlorothiazid zur Behandlung der primären arteriellen Hypertonie
In einer pragmatischen Literaturrecherche in der größten medizinischen Datenbank Medline (PubMed; US National Library of Medicine, National Institutes of Health) wurden direkte Vergleichsstudien zwischen Hydro...