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Article
Open AccessThe influence of demographic, health and psychosocial factors on patient uptake of the English NHS diabetes prevention programme
The prevention of type 2 diabetes (T2DM) is a major concern for health services around the world. The English NHS Diabetes Prevention Programme (NHS-DPP) offers a group face-to-face behaviour change interventi...
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Article
Open AccessAuthor Correction: Metacognitive Therapy versus Cognitive Behaviour Therapy in Adults with Major Depression: A Parallel Single-Blind Randomised Trial
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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Article
Open AccessMetacognitive Therapy versus Cognitive Behaviour Therapy in Adults with Major Depression: A Parallel Single-Blind Randomised Trial
In the last forty years therapy outcomes for depression have remained the same with approximately 50% of patients responding to treatments. Advances are urgently required. We hypothesised that a recent treatme...
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Article
Open AccessA randomised controlled trial of hearing and vision support in dementia: Protocol for a process evaluation in the SENSE-Cog trial
Optimising hearing and vision function may be important in improving a range of outcomes for people living with dementia (PwD) and their companions. The SENSE-Cog cross-national randomised controlled trial (RC...
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Article
Open AccessCorrection to: The comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort
The original article [1] contains an omitted grant acknowledgement and affiliation as relates to the contribution of co-author, Rafael Perera-Salazar. As such, the following two amendments should apply to the ...
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Chapter and Conference Paper
Applying Deep Learning to Predicting Dementia and Mild Cognitive Impairment
Dementia has a large negative impact on the global healthcare and society. Diagnosis is rather challenging as there is no standardised test. The purpose of this paper is to conduct an analysis on ADNI data and...
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Chapter and Conference Paper
Mesh-Based Design to Fabrication Workflows for Funicular Structures: A Case Study
Funicular shells have found large interest amongst architectural designers for their advantageous structural properties allowing them to cover large spans through the use of relatively weak and readily-availab...
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Article
Open AccessThe comorbidity burden of type 2 diabetes mellitus: patterns, clusters and predictions from a large English primary care cohort
The presence of additional chronic conditions has a significant impact on the treatment and management of type 2 diabetes (T2DM). Little is known about the patterns of comorbidities in this population. The aim...
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Article
Production of deuterated biomass by cultivation of Lemna minor (duckweed) in D2O
Common duckweed Lemna minor was cultivated in 50% D2O to produce biomass with 50–60% deuterium incorporation containing cellulose with degree of polymerization close (85%) to that of H2O-grown controls.
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Article
Open AccessIndividualised sensory intervention to improve quality of life in people with dementia and their companions (SENSE-Cog trial): study protocol for a randomised controlled trial
Hearing and vision impairments are highly prevalent in people with dementia and may have a negative impact on quality of life and other dementia-related outcomes. Intervening to optimise sensory impairment and...
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Article
MayaVault—a Mesh Modelling Environment for Discrete Funicular Structures
The didactic and fabrication related value of a geometric form-finding method such as Thrust Network Analysis(TNA) has already been established through RhinoVault. However, it also serves as the origin of our ...
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Article
Open AccessMetacognitive therapy home-based self-help for cardiac rehabilitation patients experiencing anxiety and depressive symptoms: study protocol for a feasibility randomised controlled trial (PATHWAY Home-MCT)
Anxiety and depression are common among patients attending cardiac rehabilitation services. Currently available pharmacological and psychological interventions have limited effectiveness in this population. Th...
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Article
Open AccessIs telephone health coaching a useful population health strategy for supporting older people with multimorbidity? An evaluation of reach, effectiveness and cost-effectiveness using a ‘trial within a cohort’
Innovative ways of delivering care are needed to improve outcomes for older people with multimorbidity. Health coaching involves ‘a regular series of phone calls between patient and health professional to prov...
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Article
Open AccessEffect of health literacy on the quality of life of older patients with long-term conditions: a large cohort study in UK general practice
The levels of health literacy in patients with long-term conditions (LTCs) are critical for better disease management and quality of life (QoL). However, the impact of health literacy on QoL in older adults wi...
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Article
Open AccessDevelo** a core outcome set for people living with dementia at home in their neighbourhoods and communities: study protocol for use in the evaluation of non-pharmacological community-based health and social care interventions
The key aim of the study is to establish an agreed standardised core outcome set (COS) for use when evaluating non-pharmacological health and social care interventions for people living at home with dementia.
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Article
Open AccessImproving the effectiveness of psychological interventions for depression and anxiety in the cardiac rehabilitation pathway using group-based metacognitive therapy (PATHWAY Group MCT): study protocol for a randomised controlled trial
Anxiety and depression are prevalent among cardiac rehabilitation patients but pharmacological and psychological treatments have limited effectiveness in this group. Furthermore, psychological interventions ha...
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Article
Open AccessCorrection to: Effectiveness and safety of vitamin K antagonists and new anticoagulants in the prevention of thromboembolism in atrial fibrillation in older adults – a systematic review of reviews and the development of recommendations to reduce inappropriate prescribing
After publication of the original article [1] it was found that author Marc Krause’s name had been spelt incorrectly.
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Article
Open AccessEfficacy and safety of metformin in the management of type 2 diabetes mellitus in older adults: a systematic review for the development of recommendations to reduce potentially inappropriate prescribing
Metformin is usually prescribed as first line therapy for type 2 diabetes mellitus (DM2). However, the benefits and risks of metformin may be different for older people. This systematic review examined the ava...
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Article
Open AccessEffectiveness and safety of beta blockers in the management of hypertension in older adults: a systematic review to help reduce inappropriate prescribing
The benefit from a blood pressure lowering therapy with beta blockers may not outweigh its risks, especially in older populations. The aim of this study was to look for evidence on risks and benefits of beta bloc...
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Article
Open AccessA set of systematic reviews to help reduce inappropriate prescribing to older people: study protocol
Multimorbidity and polypharmacy are common in older people. Assessment tools or lists of criteria aimed at supporting prescription decisions for older people exist, but have often been based on expert opinion ...
