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Open AccessThe use of individual-based FDG-PET volume of interest in predicting conversion from mild cognitive impairment to dementia
Based on a longitudinal cohort design, the aim of this study was to investigate whether individual-based 18F fluorodeoxyglucose positron emission tomography (18F-FDG-PET) regional signals can predict dementia con...
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Open AccessCingulate white matter mediates the effects of fecal Ruminococcus on neuropsychiatric symptoms in patients with amyloid-positive amnestic mild cognitive impairment
Microbiota-gut-brain axis interacts with one another to regulate brain functions. However, whether the impacts of gut dysbiosis on limbic white matter (WM) tracts contribute to the neuropsychiatric symptoms (N...
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Evolution and Diversity of Bioluminescent Fungi
Bioluminescence is one of the most fascinating features of basidiomycetes. In this chapter, we have reviewed a total of 105 bioluminescent fungi that have been documented to date. We show that these species ar...
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Article
Correction to: Plastome phylogenomics of Allaeanthus, Broussonetia and Malaisia (Dorstenieae, Moraceae) and the origin of B. × kazinoki
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Plastome phylogenomics of Allaeanthus, Broussonetia and Malaisia (Dorstenieae, Moraceae) and the origin of B. × kazinoki
Species of Broussonetia have been essential in the development of papermaking technology. In Japan and Korea, a hybrid between B. monoica and B. papyrifera (= B. × kazinoki) known as kōzo and daknamu is still the...
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Aleurodiscus bicornis and A. formosanus spp. nov. (Basidiomycota) with smooth basidiospores, and redescription of A. parvisporus
Three species of Aleurodiscus s.l. characterized in having effused basidiomata, clamped generative hyphae and quasi-binding hyphae, sulphuric positive reaction of gloeocystidia, hyphidia, acanthophyses, and smoot...
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Open AccessEffectiveness of the 10 cm2 Rivastigmine Patch in Taiwanese Patients with Mild-to-Moderate Alzheimer’s Dementia: A 48-Week Real-World Observational Study
The current study aimed to provide data on the effectiveness of the 10 cm2 rivastigmine patch in patients with Alzheimer’s disease (AD) in a real-world setting in Taiwan.
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Detection of Alzheimer’s disease using ECD SPECT images by transfer learning from FDG PET
To develop a practical method to rapidly utilize a deep learning model to automatically extract image features based on a small number of SPECT brain perfusion images in general clinics to objectively evaluate...
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Four new species of Phylloporia (Hymenochaetales, Basidiomycota) from southeastern Taiwan
Four new species of Phylloporia (Hymenochaetales) are presented based on collections made from subtropical-tropical southeastern Taiwan. They are P. alyxiae, P. mori, P. murrayae, and P. rubiacearum. These four s...
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Open AccessSix new species of Begonia from Guangxi, China
With currently 1980 described species, the mega-diverse Begonia is now perhaps the 5th largest flowering plant genus, expanding rapidly from ca. 900 species in 1997 to its current size in merely two decades. In c...
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Open AccessPlasma amyloid assay as a pre-screening tool for amyloid positron emission tomography imaging in early stage Alzheimer’s disease
Due to the high cost and high failure rate of ascertaining amyloid positron emission tomography positivity (PET+) in patients with earlier stage Alzheimer’s disease (AD), an effective pre-screening tool for am...
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Open AccessABCA7 polymorphisms correlate with memory impairment and default mode network in patients with APOEε4-associated Alzheimer’s disease
Since both APOE and ABCA7 protein expression may independently reduce neuritic plaque burden and reorganize fibrillar amyloid burden-mediated disruption of functional connectivity in the default mode network, we ...
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A 48-Week, Multicenter, Open-Label, Observational Study Evaluating Oral Rivastigmine in Patients with Mild-to-Moderate Alzheimer’s Disease in Taiwan
Rivastigmine is a cholinesterase inhibitor, approved for the treatment of mild-to-moderate dementia of Alzheimer’s type. This study assessed the short- and long-term effectiveness and safety of rivastigmine in...
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MAOA-VNTR Genotype Effects on Ventral Striatum-Hippocampus Network in Alzheimer’s Disease: Analysis Using Structural Covariance Network and Correlation with Neurobehavior Performance
Functional polymorphisms in the promoter region of the monoamine oxidase A (MAOA) gene are associated with brain MAOA activity and transcriptional efficiency in patients with Alzheimer’s disease (AD). This study ...
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Open AccessRisk of dementia in patients with end-stage renal disease under maintenance dialysis—a nationwide population-based study with consideration of competing risk of mortality
Dementia is prevalent in the end-stage renal disease (ESRD) population. However, it is still not clarified whether ESRD is one of the etiology of dementia or its attributable effect on the cumulative risk of d...
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Open AccessThe clinical characteristics and therapeutic outcomes of cryptococcal meningitis in elderly patients: a hospital-based study
The elderly, and especially those with an immuno-compromised status, are vulnerable to infectious diseases. The purpose of this study was to examine the clinical characteristics and therapeutic outcomes of cry...
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Open AccessCatechol-O-Methyltransferase Val158Met Polymorphism on Striatum Structural Covariance Networks in Alzheimer’s Disease
The catechol-O-methyltransferase enzyme metabolizes dopamine in the prefrontal axis, and its genetic polymorphism (rs4680; Val158Met) is a known determinant of dopamine signaling. In this study, we investigate...
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Open AccessAssociations of Bcl-2 rs956572 genotype groups in the structural covariance network in early-stage Alzheimer’s disease
Alzheimer’s disease (AD) is a complex neurodegenerative disease, and genetic differences may mediate neuronal degeneration. In humans, a single-nucleotide polymorphism in the B-cell chronic lymphocytic leukemi...
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Open AccessCerebral Perfusion Insufficiency and Relationships with Cognitive Deficits in Alzheimer’s Disease: A Multiparametric Neuroimaging Study
Micro- or macro-circulatory insufficiency has a negative impact in patients with Alzheimer’s disease (AD). This study used arterial spin-labeled magnetic resonance imaging (ASL-MRI) and ethylcysteinate dimer s...
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Open AccessEffects of Homocysteine on white matter diffusion parameters in Alzheimer’s disease
The clinical features of Alzheimer’s disease (AD) are related to brain network degeneration, and hyperhomocysteinemia is related to greater white matter hyperintensities. We investigated the changes in four di...
