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    Article

    SViMULATE: a computer program facilitating interactive, multi-mode simulation of analytical ultracentrifugation data

    The ability to simulate sedimentation velocity (SV) analytical ultracentrifugation (AUC) experiments has proved to be a valuable tool for research planning, hypothesis testing, and pedagogy. Several options fo...

    Chad A. Brautigam in European Biophysics Journal (2023)

  2. Article

    Open Access

    Correction to: Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

    Blanca López-Méndez, Bruno Baron, Chad A. Brautigam in European Biophysics Journal (2021)

  3. Article

    Open Access

    Reproducibility and accuracy of microscale thermophoresis in the NanoTemper Monolith: a multi laboratory benchmark study

    Microscale thermophoresis (MST), and the closely related Temperature Related Intensity Change (TRIC), are synonyms for a recently developed measurement technique in the field of biophysics to quantify biomolec...

    Blanca López-Méndez, Bruno Baron, Chad A. Brautigam in European Biophysics Journal (2021)

  4. No Access

    Article

    Using modern approaches to sedimentation velocity to detect conformational changes in proteins

    It has been known for decades that proteins undergo conformational changes in response to binding ligands. Such changes are usually accompanied by a loss of entropy by the protein, and thus conformational chan...

    Chad A. Brautigam, Shih-Chia Tso, Ranjit K. Deka, Wei Z. Liu in European Biophysics Journal (2020)