-
Article
Pflanzliche Arzneimittel
Pflanzliche Arzneimittel sind beliebt. Die Vorstellung, dass sie wirksam und sicher sind, ist verbreitet. Solide Kenntnisse über bislang vorliegende sowie immer noch fehlende Daten zur Wirksamkeit und Sicherhe...
-
Article
Impaired Synthesis of Erythropoietin, Glutamine Synthetase and Metallothionein in the Skin of NOD/SCID/γ c null and Foxn1 nu/nu Mice with Misbalanced Production of MHC Class II Complex
Most skin pathologies are characterized by unbalanced synthesis of major histocompatability complex II (MHC-II) proteins. Healthy skin keratinocytes simultaneously produce large amounts of MHC-II and regenerat...
-
Article
Survival, neuron-like differentiation and functionality of mesenchymal stem cells in neurotoxic environment: the critical role of erythropoietin
Mesenchymal stem cells (MSCs) can ameliorate symptoms in several neurodegenerative diseases. However, the toxic environment of a degenerating central nervous system (CNS) characterized by hypoxia, glutamate (G...
-
Article
Effect of endothelin-1 on erythropoietin production in a rat model under normoxia and functional carbon monoxide-induced hypoxia
It has been hypothesized that autacoids, such as endothelin-1 (ET), may modulate erythropoietin (Epo) secretion. Therefore, we studied the effect of ET-1 infusion and of a nonselective ETA/B receptor antagonist o...
-
Chapter
Sonstige psychotrope Substanzen
Koffein (1,3,7-Trimethylxanthin; C8H10N4O12, Molekulargewicht 194,19) gehört zur Gruppe der natürlich vorkommenden Purine wie die strukturähnlichen Theophyllin (1,3-Dimethylxanthin) und Theobromin (3,7-Dimethylxa...
-
Article
Letter to the editor concerning Ufer et al.: Eur J Clin Pharmacol 58:779–783 (2003)
-
Article
Arzneimittel und Fahrsicherheit
-
Article
Pflanzliche Arzneimittel
Die Verwendung pflanzlicher Arzneimittel ist nicht frei von Risiken. Obwohl diese Tatsache in medizinischen Fachkreisen zunehmend wahrgenommen wird, ist sie bei Laien noch wenig bekannt. Neben eigenen unerwüns...
-
Article
Off-Label-Verordnungen in der Pädiatrie
-
Article
Arzneimittel und Teilnahme am Straßenverkehr
-
Article
Beeinflussung der Fahrtüchtigkeit durch Arzneimittel
-
Article
Tiefe Beinvenenthrombose in der Schwangerschaft
-
Article
Dose-dependent effect of angiotensin II on human erythropoietin production
Current evidence suggests that angiotensin II may be involved in the regulation of renal erythropoietin (EPO) production. The present study assessed the role of angiotensin II (A II) in different doses in the ...
-
Article
Kinetics and characteristics of an acute phase response following cardiac arrest
Objective: Inflammation and hypoxia are frequently associated, but their interaction is poorly understood. In vitro studies have shown that hypoxia stimulates the genes of acute phase proteins (APP) and cytokines...
-
Article
Renal response to infusion of dopamine precursors in anaesthetized rats
In the present study the renal response to intravenous infusion of the catecholamine precursors l-dihydroxyphenylalanine (l-DOPA) or l-tyrosine was investigated in thiopentone sodium-anaesthetized Sprague-Dawley ...
-
Article
Non-response to maprotiline caused by ultra-rapid metabolism that is different from CYP2D6?
Case: We are reporting about a patient with major depression who failed to respond to pharmacotherapy due to ultra-rapid metabolism of maprotiline. Under daily oral doses of 175 mg mapro...
-
Article
Paracetamol — das sichere Analgetikum
-
Article
Influence of food intake on the bioavailability of thioctic acid enantiomers
-
Article
Gender differences in pharmacokinetics
The is growing awareness that the underrepresentation of women in clinical trials and in particular in phase I studies may lead to incorrect handling of drugs. Despite the fact that investigations are not perf...
-
Article
Brofaromine — a review of its pharmacological properties and therapeutic use
The antidepressant activity of monoamine oxidase inhibitors has been well established for 30 years. Nevertheless, this group of compounds was handled with great care, mainly because of the interaction potentia...