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Article
Chemotherapy in advanced ovarian cancer
The chemotherapy of advanced ovarian cancer is reviewed. Treatment with single agents results in low remission rates and few complete remissions. The results have been improved with modern combination chemothe...
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Chapter
Chemotherapy
The history of cancer chemotherapy started with the incidental discovery that nitrogen mustard was cytotoxic to lymphoid malignancies. The initial enthusiasm was soon tempered by the observation that most resp...
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Chapter
Chemotherapy in Disseminated Testicular Cancer
Testicular germ cell tumours can be divided into seminomas and non-seminomas. Seminomas are radiosensitive and approximately 90% can be cured with radiotherapy since, in the majority of cases, the disease is l...
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Article
Occurrence of epidermal growth factor receptors in benign and malignant ovarian tumors and normal ovarian tissues: an immunohistochemical study
Epidermal growth factor receptor (EGF-R) was studied with monoclonal antibody 2E9 on 50 ovarian tumors of various histological types and 10 non-tumorous ovarian tissues by immunohistochemistry. Enhanced expres...
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Article
Weekly low-dose mitoxantrone plus doxorubicin as second-line chemotherapy for advanced breast cancer
Weekly low dose mitoxantrone (3 mg/m2) plus doxorubicin (8 mg/m2) was administered as second-line chemotherapy to 33 patients with advanced breast cancer. Four out of 28 evaluable patients (14%) obtained a partia...
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Article
The effects of an ACTH (4–9) analogue on development of cisplatin neuropathy in testicular cancer: A randomized trial
The efficacy of the ACTH (4–9) analogue Org 2766 in the prevention of subclinical cisplatin neuropathy was assessed in a double-blind placebo-controlled multi-centre study in patients with testicular cancer or...
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Article
Venous thrombosis as a complication of antiemetic treatment
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Chapter
Oncologie
In dit hoofdstuk, waarin solide tumoren worden besproken, wordt eerst kort ingegaan op de epidemiologie en etiologie. Vervolgens komen algemene aspecten van diagnostiek, stagering en therapie aan de orde.
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Article
Epirubicin and paclitaxel with G-CSF support in first line metastatic breast cancer: a randomized phase II study of dose-dense and dose-escalated chemotherapy
An increased dose-intensity can be achieved by either higher dose of chemotherapy per cycle (dose-escalation) or by shortening the interval between cycles (dose-dense). This multicenter randomized phase II stu...
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Article
Open AccessCancer survivors’ needs during various treatment phases after multimodal treatment for colon cancer - is there a role for eHealth?
More colon cancer patients are expected to fully recover after treatment due to earlier detection of cancer and improvements in general health- and cancer care. The objective of this study was to gather partic...