17 Result(s)
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Brian J. Bartholmai
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Chapter and Conference Paper
Deep Learning-Based Air Trap** Quantification Using Paired Inspiratory-Expiratory Ultra-low Dose CT
Air trap** (AT) is a frequent finding in early cystic fibrosis (CF) lung disease detectable by imaging. The correct radiographic assessment of AT on paired inspiratory-expiratory computed tomography (CT) sca...
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Article
Lung vessel volume evaluated with CALIPER software is an independent predictor of mortality in COVID-19 patients: a multicentric retrospective analysis
Computer-Aided Lung Informatics for Pathology Evaluation and Ratings (CALIPER) software has already been widely used in the evaluation of interstitial lung diseases (ILD) but has not yet been tested in patient...
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Article
Correction to: Vessel-related structures predict UIP pathology in those with a non-IPF pattern on CT
A Correction to this paper has been published: https://doi.org/10.1007/s00330-021-08017-2
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Article
Vessel-related structures predict UIP pathology in those with a non-IPF pattern on CT
To determine if a quantitative imaging variable (vessel-related structures [VRS]) could identify subjects with a non-IPF diagnosis CT pattern who were highly likely to have UIP histologically.
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Article
Stratification of long-term outcome in stable idiopathic pulmonary fibrosis by combining longitudinal computed tomography and forced vital capacity
To test HRCT with either visual or quantitative analysis in both short-term and long-term follow-up of stable IPF against long-term (transplant-free) survival, beyond 2 years of disease stability.
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Article
Open AccessSpirometric assessment of emphysema presence and severity as measured by quantitative CT and CT-based radiomics in COPD
The mechanisms underlying airflow obstruction in COPD cannot be distinguished by standard spirometry. We ascertain whether mathematical modeling of airway biomechanical properties, as assessed from spirometry,...
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Article
Open AccessStatin as a novel pharmacotherapy of pulmonary alveolar proteinosis
Pulmonary alveolar proteinosis (PAP) is a syndrome of reduced GM-CSF-dependent, macrophage-mediated surfactant clearance, dysfunctional foamy alveolar macrophages, alveolar surfactant accumulation, and hypoxem...
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Article
Serial automated quantitative CT analysis in idiopathic pulmonary fibrosis: functional correlations and comparison with changes in visual CT scores
To determine whether computer-based CT quantitation of change can improve on visual change quantification of parenchymal features in IPF.
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Article
Open AccessComputer-Aided Nodule Assessment and Risk Yield (CANARY) may facilitate non-invasive prediction of EGFR mutation status in lung adenocarcinomas
Computer-Aided Nodule Assessment and Risk Yield (CANARY) is quantitative imaging analysis software that predicts the histopathological classification and post-treatment disease-free survival of patients with a...
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Article
Novel Assessment of Interstitial Lung Disease Using the “Computer-Aided Lung Informatics for Pathology Evaluation and Rating” (CALIPER) Software System in Idiopathic Inflammatory Myopathies
To evaluate the correlation between measurements from quantitative thoracic high-resolution CT (HRCT) analysis with “Computer-Aided Lung Informatics for Pathology Evaluation and Rating” (CALIPER) software and ...
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Article
Open AccessChronic hypersensitivity pneumonitis: identification of key prognostic determinants using automated CT analysis
Chronic hypersensitivity pneumonitis (CHP) has a variable disease course. Computer analysis of CT features was used to identify a subset of CHP patients with an outcome similar to patients with idiopathic pulm...
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Article
Open AccessEvaluation of computer-based computer tomography stratification against outcome models in connective tissue disease-related interstitial lung disease: a patient outcome study
To evaluate computer-based computer tomography (CT) analysis (CALIPER) against visual CT scoring and pulmonary function tests (PFTs) when predicting mortality in patients with connective tissue disease-related...
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Article
Sensitivity of Thoracic Digital Tomosynthesis (DTS) for the Identification of Lung Nodules
Thoracic computed tomography (CT) is considered the gold standard for detection lung pathology, yet its efficacy as a screening tool in regards to cost and radiation dose continues to evolve. Chest radiography...
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Article
Active Relearning for Robust Supervised Training of Emphysema Patterns
Radiologists are adept at recognizing the character and extent of lung parenchymal abnormalities in computed tomography (CT) scans. However, the inconsistent differential diagnosis due to subjective aggregatio...
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Chapter and Conference Paper
Referenceless Stratification of Parenchymal Lung Abnormalities
This paper introduces computational tools that could enable personalized, predictive, preemptive, and participatory (P4) Pulmonary medicine. We demonstrate approaches to (a) stratify lungs from different subje...
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Article
Open AccessIron deposition and increased alveolar septal capillary density in nonfibrotic lung tissue are associated with pulmonary hypertension in idiopathic pulmonary fibrosis
Early diagnosis of pulmonary hypertension (PH) in idiopathic pulmonary fibrosis (IPF) has potential prognostic and therapeutic implications but can be difficult due to the lack of specific clinical manifestati...
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Article
Effect of Automated Image Registration on Radiologist Interpretation
In this study, we present preliminary data on the effect of automated 3D image alignment on the time to arrive at a decision about an imaging finding, the agreement of multiple of multiple observers, the preva...
