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  1. Article

    Open Access

    Primary immunodeficiency diseases of adults: a review of pulmonary complication imaging findings

    Our objective in this review is to familiarize radiologists with the spectrum of initial and progressive CT manifestations of pulmonary complications observed in adult patients with primary immunodeficiency di...

    Philippe A. Grenier, Anne Laure Brun, Elisabeth Longchampt in European Radiology (2024)

  2. Article

    COVID-19 pneumonia: high diagnostic accuracy of chest CT in patients with intermediate clinical probability

    To assess inter-reader agreements and diagnostic accuracy of chest CT to identify COVID-19 pneumonia in patients with intermediate clinical probability during an acute disease outbreak.

    Anne Laure Brun, Alexia Gence-Breney, Julie Trichereau in European Radiology (2021)

  3. Article

    Tocilizumab for Severe Worsening COVID-19 Pneumonia: a Propensity Score Analysis

    High levels of serum interleukin-6 (IL-6) correlate with disease severity in COVID-19. We hypothesized that tocilizumab (a recombinant humanized anti-IL-6 receptor) could improve outcomes in selected patients ...

    Mathilde Roumier, Romain Paule, Alexandre Vallée in Journal of Clinical Immunology (2021)

  4. Article

    Open Access

    Imaging features and differential diagnoses of non-neoplastic diffuse mediastinal diseases

    Acute or chronic non-neoplastic diffuse mediastinal diseases have multiple causes, degrees of severity, and a wide range of management. Some situations require emergency care while others do not need specific ...

    Flavian Tabotta, Gilbert R. Ferretti, Helmut Prosch in Insights into Imaging (2020)

  5. No Access

    Article

    Serial automated quantitative CT analysis in idiopathic pulmonary fibrosis: functional correlations and comparison with changes in visual CT scores

    To determine whether computer-based CT quantitation of change can improve on visual change quantification of parenchymal features in IPF.

    Joseph Jacob, Brian J. Bartholmai, Srinivasan Rajagopalan in European Radiology (2018)

  6. Article

    Open Access

    Chronic hypersensitivity pneumonitis: identification of key prognostic determinants using automated CT analysis

    Chronic hypersensitivity pneumonitis (CHP) has a variable disease course. Computer analysis of CT features was used to identify a subset of CHP patients with an outcome similar to patients with idiopathic pulm...

    Joseph Jacob, Brian J. Bartholmai, Ryoko Egashira in BMC Pulmonary Medicine (2017)

  7. Article

    Open Access

    Evaluation of computer-based computer tomography stratification against outcome models in connective tissue disease-related interstitial lung disease: a patient outcome study

    To evaluate computer-based computer tomography (CT) analysis (CALIPER) against visual CT scoring and pulmonary function tests (PFTs) when predicting mortality in patients with connective tissue disease-related...

    Joseph Jacob, Brian J. Bartholmai, Srinivasan Rajagopalan, Anne Laure Brun in BMC Medicine (2016)

  8. No Access

    Chapter

    Non-langerhans Cell Histiocytosis-Including Erdheim-Chester Disease- and the Lung

    Erdheim-Chester disease (ECD) is a rare form of non–Langerhans’ cell histiocytosis that may present with pulmonary involvement. The disease was first described as the “lipoid granulomatose” in 1930. Between th...

    Julien Haroche, Anne-Laure Brun, Frédérique Capron in Orphan Lung Diseases (2015)

  9. No Access

    Article

    Erdheim-Chester disease: CT findings of thoracic involvement

    To retrospectively assess the association of mediastinal, cardiovascular and pleuropulmonary findings on chest CT of 40 patients with immunohistochemically and histologically proven Erdheim-Chester disease (ECD).

    Anne-Laure Brun, Diane Touitou-Gottenberg, Julien Haroche in European Radiology (2010)