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Open AccessEvidences of in vivo cytotoxic and apoptotic potential of anthelmintic phytochemical kaempferol derivative isolated from Lysimachia ramosa (Wall. ex Duby) in Wistar rats
Lysimachia ramosa (Wall. ex Duby) is a traditionally used medicinal plant in Meghalaya, a northeastern state of India. The people use the leaves of the plant to cure gastrointestinal worm infection. Kaempferol de...
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Article
Anthelmintic Efficacy of Solanum spirale on Fowl Tapeworm, Raillietina echinobothrida
The goal of this study was to investigate the in vitro anthelmintic efficacy of methanolic leaf extract of Solanum spirale (Solanaceae), a traditionally used anthelmintic plant in India, on poultry gastrointestin...
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Article
Secondary Structure Analysis of Fasciola from Semi-wild Ruminants of Northeast India
The objective of this study is to study the secondary structure analysis of Fasciola flukes from a rare mithun host from Manipur. Fascioliasis, a neglected tropical trematodiasis, is poorly studied in India and i...
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Article
In vitro cestocidal activity of Persicaria hydropiper (L.) Delarbre, a traditionally used anthelmintic plant in India
Persicaria hydropiper is a medicinal plant used for the treatment of helminth infections among the Naga people of India. To verify the traditional claim of the plant, an in vitro anthelmintic efficacy of the meth...
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Article
Chitosan-gold nanoparticles trigger apoptosis in human breast cancer cells in vitro
Despite profound advancement in the field of cancer treatment, the disease is still one of the deadliest in the world. In this aspect, nanotechnology is emerging as a highly promising area to be focussed upon....
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Surface-Modified Noble Metal Nanoparticles as Antimicrobial Agents: Biochemical, Molecular and Therapeutic Perspectives
Despite the progress of the development of antimicrobial therapeutics, the whole world is still under pressure of several microbial diseases. Antimicrobial drug development is therefore considered as one of th...
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Article
Effect of Lysimachia ramosa Wall. Ex Duby and Its n-Butanol Fraction on Glycogen Content and Some Energy Related Enzymes in the Cestode, Raillietina echinobothrida
The current investigation aims to evaluate the effect of leaf extract of the anthelmintic medicinal plant Lysimachia ramosa and its n-butanol fraction on glycogen concentration and carbohydrate related metabolic ...
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Article
Cytotoxic effect of green synthesized silver nanoparticles in MCF7 and MDA-MB-231 human breast cancer cells in vitro
With the incessant rise in the cancer burden worldwide it is a dire need to develop anticancer agents that will offer negligible or no side effects and at the same time will be economically feasible. In this s...
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Millettia Pachycarpa Benth: A Herbal Medicinal Plant of Southeast Asia
Plants and plant products are constituent parts of the inventory of drugs since time immemorial. Millettia pachycarpa (Family: Fabaceae) is widely seen in India, Bangladesh, Bhutan, Myanmar, China, Taiwan, and Ja...
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Article
Molecular identification of two cestodes species parasitizing freshwater fishes in India
In the present study, molecular identification of two species of cestodes, Lytocestus indicus and Senga lucknowensis infecting freshwater fishes Clarias magur and Channa punctata, respectively in Manipur is carri...
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Chapter
Amphistomes
Amphistomes, commonly referred to as ‘stomach’ or ‘rumen’ flukes because of the localization of these flukes in the stomach of ruminants, are digenetic trematodes distinguished by the absence of an oral sucker...
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Article
Chitosan biopolymer functionalized gold nanoparticles with controlled cytotoxicity and improved antifilarial efficacy
Ultra-high stable chitosan functionalized gold nanoparticles (GNPs) of desired biopolymeric corona are synthesized without adding conventional hazardous reducing agents. The inherent unique set of properties l...
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Article
Biochemical and ultrastructural changes in Raillietina echinobothrida in vitro exposed to extract of Lysimachia ramosa
Lysimachia ramosa (Primulaceae) is a traditionally used medicinal plant, leaves extract of which is being widely used by the Jaintia tribes of Meghalaya, India for controlling helminthiasis. Preliminary investiga...
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Article
Differential diagnosis and molecular characterization of Hymenolepis nana and Hymenolepis diminuta (Cestoda: Cyclophyllidea: Hymenolepididae) based on nuclear rDNA ITS2 gene marker
Given the widespread distribution and medical implication of members of the genus Hymenolepis, specific identification of the aetiological agent becomes imperative. For precise diagnosis of the species, molecular...
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Article
Molecular phylogeny of Cyclophyllidea (Cestoda: Eucestoda): an in-silico analysis based on mtCOI gene
Order Cyclophyllidea (of cestode platyhelminths) has a rich diversity of parasites and includes many families and species that are known to cause serious medical condition in humans and domestic and wild anima...
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Article
Cysticercus fasciolaris infection induced oxidative stress and apoptosis in rat liver: a strategy for host-parasite cross talk
Parasitic helminths have developed various strategies to induce or inhibit apoptosis in the cells of their host, thereby modulating the host’s immune response and aiding dissemination to the host. Cysticercus fas...
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Article
Filarial infections in semi-wild cattle of Northeast India: first record of Setaria digitata (von Linstow 1906) in Bos frontalis (Lambert 1804)
The occurrence of adult Setaria digitata, a filarial nematode of bovine host is reported for the first time from mithun (Bos frontalis) of Arunachal Pradesh, India. During December 2011 to March 2012, a thorough ...
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Article
Resveratrol- and α-viniferin-induced alterations of acetylcholinesterase and nitric oxide synthase in Raillietina echinobothrida
Phytostilbenes, like resveratrol and α-viniferin, which occur mainly in the plants and belong to the families Cyperaceae, Vitaceae, and Gnetaceae are extensively popular for their medicinal and nutritional pro...
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Article
In vivo anthelmintic activity of Carex baccans and its active principle resveratrol against Hymenolepis diminuta
Anthelmintic resistance against most of the commercial drugs is a great threat to humans as well as the veterinary live stocks. Hence, new treatment strategies to control helminth infections are essential at t...
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Chapter
Amphistomes
Amphistomes, commonly referred to as ‘stomach’ or ‘rumen’ flukes because of the localization of these flukes in the stomach of ruminants, are digenetic trematodes distinguished by the absence of an oral sucker...