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  1. No Access

    Article

    Positive rate and quantification of amyloid pathology with [18F]florbetapir in the urban Chinese population

    Amyloid deposition is considered the initial pathology in Alzheimer’s disease (AD). Personalized management requires investigation of amyloid pathology and the risk factors for both amyloid pathology and cogni...

    Kun He, Binyin Li, Lin Huang, Jun Zhao, Fengchun Hua, Tao Wang… in European Radiology (2024)

  2. No Access

    Article

    Tau pathology is associated with synaptic density and longitudinal synaptic loss in Alzheimer’s disease

    The associations of synaptic loss with amyloid-β (Aβ) and tau pathology measured by positron emission tomography (PET) and plasma analysis in Alzheimer’s disease (AD) patients are unknown. Seventy-five partici...

    Jie Wang, Qi Huang, **ng Chen, Zhiwen You, Kun He, Qihao Guo… in Molecular Psychiatry (2024)

  3. Article

    Open Access

    Correction to: Adaptive structural changes in the motor cortex and white matter in Parkinson’s disease

    YuHong Fu, Liche Zhou, Hongyun Li, Jen‑Hsiang T. Hsiao, Binyin Li… in Acta Neuropathologica (2023)

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  4. Article

    Open Access

    Adaptive structural changes in the motor cortex and white matter in Parkinson’s disease

    Parkinson’s disease (PD) is a movement disorder characterized by the early loss of nigrostriatal dopaminergic pathways producing significant network changes impacting motor coordination. Recently three motor s...

    YuHong Fu, Liche Zhou, Hongyun Li, Jen-Hsiang T. Hsiao, Binyin Li… in Acta Neuropathologica (2022)

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  5. No Access

    Article

    Altered intrinsic brain activity in patients with CSF1R-related leukoencephalopathy

    CSF1R-related leukoencephalopathy is an adult-onset white matter disease with high disability and mortality, while little is known about its pathogenesis. This study introduced amplitude of low-frequency fluctuat...

    **gying Wu, Yikang Cao, Mengting Li, Binyin Li, **ze Jia… in Brain Imaging and Behavior (2022)

  6. Article

    Open Access

    Increased prediction value of biomarker combinations for the conversion of mild cognitive impairment to Alzheimer’s dementia

    Progression of mild cognitive impairment (MCI) to Alzheimer’s disease (AD) dementia can be predicted by clinical features and a combination of biomarkers may increase the predictive power. In the present study...

    Aonan Zhao, Yuanyuan Li, Yi Yan, Yinghui Qiu, Binyin Li… in Translational Neurodegeneration (2020)

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  7. Article

    Open Access

    Shanghai cognitive intervention of mild cognitive impairment for delaying progress with longitudinal evaluation-a prospective, randomized controlled study (SIMPLE): rationale, design, and methodology

    Mild cognitive impairment is an early stage of Alzheimer’s disease. Increasing evidence has indicated that cognitive training could improve cognitive abilities of MCI patients in multiple cognitive domains, ma...

    Yiqi Lin, Binyin Li, Huidong Tang, Qun Xu, Yuncheng Wu, Qi Cheng… in BMC Neurology (2018)

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