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Article
Open AccessMultiple cancer cell types release LIF and Gal3 to hijack neural signals
Neural signals can significantly influence cancer prognosis. However, how cancer cells may proactively modulate the nervous system to benefit their own survival is incompletely understood. In this study, we re...
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Article
Open AccessA survey on lattice-based digital signature
Lattice-based digital signature has become one of the widely recognized post-quantum algorithms because of its simple algebraic operation, rich mathematical foundation and worst-case security, and also an impo...
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Article
Association Between Metal Exposure and Mitochondrial DNA Parameters and the Potential Mediation Effect of Oxidative Stress
The possible mechanism of metal toxicity is oxidative stress and mitochondrial DNA damage. However, the association between environmental metal exposure and mitochondrial DNA damage and the potential mediators...
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Article
Differential effects of PM2.5 and its carbon components on blood pressure in hypertensive and non-hypertensive populations: a panel study in Bei**g
Published literature considering the association between ambient air pollution and blood pressure is highly inconsistent, which may be explained by the different proportions of susceptible subpopulations. We h...
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Effects of Environmental Heavy Metal Interactions on Renal Impairment: Epidemiological Evidence from Rural Northeastern China
Chronic kidney disease, common in older individuals, causes a considerable disease burden worldwide. Although heavy metal exposure is associated with renal impairment, the effects of heavy metal mixtures and m...
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Open AccessIntegrating genome-wide association study into genomic selection for the prediction of agronomic traits in rice (Oryza sativa L.)
Accurately identifying varieties with targeted agronomic traits was thought to contribute to genetic selection and accelerate rice breeding progress. Genomic selection (GS) is a promising technique that uses m...
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Open AccessAnomalous water molecular gating from atomic-scale graphene capillaries for precise and ultrafast molecular sieving
The pressing crisis of clean water shortage requires membranes to possess effective ion sieving as well as fast water flux. However, effective ion sieving demands reduction of pore size, which inevitably hinde...
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Article
Open AccessBioinspired “cage traps” for closed-loop lead management of perovskite solar cells under real-world contamination assessment
Despite the remarkable progress made in perovskite solar cells, great concerns regarding potential Pb contamination risk and environmental vulnerability risks associated with perovskite solar cells pose a sign...
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Article
Open AccessStrong ferromagnetism of g-C3N4 achieved by atomic manipulation
Two-dimensional (2D) metal-free ferromagnetic materials are ideal candidates to fabricate next-generation memory and logic devices, but optimization of their ferromagnetism at atomic-scale remains challenging....
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Variability, Clearance, and Concentration of Multiple Metals and Risk of Kidney Function Abnormality: A New Integrative Metal Exposure Assessment Approach
Metal exposure contributes significantly to the pathogenesis of kidney dysfunction. However, most studies have focused on metal concentration in a single matrix (i.e., blood or urine), and few have explored th...
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Article
Associations and burdens of relative humidity with cause-specific mortality in three Chinese cities
This study aimed to investigate the association between relative humidity (RH) and various cause of mortality, and then quantify the RH-related mortality fraction of low and high RH under the assumption that c...
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Adjustment for body mass index changes inverse associations of HDL-cholesterol with blood pressure and hypertension to positive associations
The associations between high-density lipoprotein cholesterol (HDL-C) and blood pressure (BP) or hypertension are inconsistent in previous studies. This study aimed to assess these associations in a large coho...
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The association between urine elements and fasting glucose levels in a community-based elderly people in Bei**g
Epidemiological studies have demonstrated that various kinds of urinary element concentrations were different between healthy, prediabetes, and diabetes patients. Meanwhile, many studies have explored the rela...
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Efficacy and safety of tetracyclines for pemphigoid: a systematic review and meta-analysis
The aim of this review was to evaluate the efficacy and safety of tetracyclines for treatment of pemphigoid. We searched PubMed, EMBASE, Ovid, Web of Science, and the Cochrane Library for studies involving pem...
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Controllable printing of large-scale compact perovskite films for flexible photodetectors
Perovskite materials are promising candidates for the next generation of wearable optoelectronics. However, due to uncontrolled crystallization and the natural brittle property of crystals, it remains a great ...
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Article
Open AccessCorrection to: Validation of a QTL for Grain Size and Weight Using an Introgression Line from a Cross between Oryza sativa and Oryza minuta
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Hyperuricemia is independently associated with hypertension in men under 60 years in a general Chinese population
Hyperuricemia has been associated with hypertension, however, whether this association exists across all decades of adult life is unknown. This study aimed to assess the association between hyperuricemia and h...
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Article
The Associated Factors of Anxiety and Depressive Symptoms in COVID-19 Patients Hospitalized in Wuhan, China
This study was aimed to investigate the prevalence and factors associated with anxiety and depressive symptoms among hospitalized patients with COVID-19 during the epidemic outbreak in Wuhan, China. A total of...
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Open AccessValidation of a QTL for Grain Size and Weight Using an Introgression Line from a Cross between Oryza sativa and Oryza minuta
Grain size and weight are important target traits determining grain yield and quality in rice. Wild rice species possess substantial elite genes that can be served as an important resource for genetic improvem...
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Article
Open AccessA 36-week multicenter, randomized, double-blind, placebo-controlled, parallel-group, phase 3 clinical trial of sodium oligomannate for mild-to-moderate Alzheimer’s dementia
New therapies are urgently needed for Alzheimer’s disease (AD). Sodium oligomannate (GV-971) is a marine-derived oligosaccharide with a novel proposed mechanism of action. The first phase 3 clinical trial of G...
