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Open AccessOutcome of a de-labelling algorithm compared with results of penicillin (β-lactam) allergy testing
Penicillin allergy labels frequently impede guideline-directed treatment with a penicillin or other β-lactam antibiotics. Despite presumed allergy, targeted questioning may indicate a low probability of sensit...
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Article
Open AccessRisk factors in bee and Vespula venom allergy: state of the art
Correct recognition of risk factors enables individualized management and treatment of venom allergic patients.
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Penicillin-Toleranzinduktion in der Schwangerschaft
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Open AccessHealthcare provision for insect venom allergy patients during the COVID-19 pandemic
The population prevalence of insect venom allergy ranges between 3–5%, and it can lead to potentially life-threatening allergic reactions. Patients who have experienced a systemic allergic reaction following a...
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Open AccessPredominant patterns of β-lactam hypersensitivity in a single German Allergy Center: exanthem induced by aminopenicillins, anaphylaxis by cephalosporins
Penicillins and other β-lactam antibiotics are the most common elicitors of allergic drug reaction. However, data on the pattern of clinical reaction types elicited by specific β-lactams are scarce and inconsi...
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Article
S2k-Leitlinie: Diagnostik bei Verdacht auf eine Betalaktamantibiotika-Überempfindlichkeit
Die vorliegende Leitlinie (S2k) zur Diagnostik bei Verdacht auf eine Betalaktamantibiotika-Überempfindlichkeit wurde von den deutschen allergologischen Fachverbänden und der österreichischen allergologischen F...
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Open AccessGuideline on diagnostic procedures for suspected hypersensitivity to beta-lactam antibiotics
This guideline on diagnostic procedures for suspected beta-lactam antibiotic (BLA) hypersensitivity was written by the German and Austrian professional associations for allergology, and the Paul-Ehrlich Societ...
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Correction to: Guideline for the diagnosis of drug hypersensitivity reactions
Correction to:
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Allergic reactions to antibiotics – two sides of the same coin: clearly diagnose or reliably rule out
Antibiotics cause allergic reactions with a disproportionate frequency compared with other drugs. Skin symptoms such as exanthema usually result but systemic anaphylactic responses may also occur.
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Die zwei Seiten der „Antibiotikaallergie-Medaille“: eindeutig diagnostizieren oder sicher ausschließen
Antibiotika belegen in deutschen Verordnungsstatistiken seit Jahren Spitzenpositionen, gleichzeitig verursachen sie im Vergleich mit anderen Arzneimitteln überproportional häufig allergische Reaktionen. Meist ...
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Open AccessSafety of 100 µg venom immunotherapy rush protocols in children compared to adults
There is a paucity of studies examining the safety of venom immunotherapy (VIT) in children. We aimed to assess the incidence of anaphylactic side effects during rush VIT in a cohort of pediatric patients and ...
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Dermpath & Clinic: Multiple reactive eccrine syringofibroadenomas
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Leitlinie Allergologische Diagnostik von Überempfindlichkeitsreaktionen auf Arzneimittel
Arzneimittelüberempfindlichkeitsreaktionen sind unvorhersehbare, durch Arzneimittel hervorgerufene Reaktionen. Sie manifestieren sich entweder innerhalb von ein bis sechs Stunden nach Arzneimittelzufuhr („Sofo...
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Article
Guideline for the diagnosis of drug hypersensitivity reactions
Drug hypersensitivity reactions are unpredictable adverse drug reactions. They manifest either within 1–6 h following drug intake (immediate reactions) with mild to life-threatening symptoms of anaphylaxis, or...
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Guideline contact dermatitis
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Open AccessNon-steroidal anti-inflammatory drug hypersensitivity: association with elevated basal serum tryptase?
It is hypothesized that because of higher mast cell numbers and mediator release, mastocytosis predisposes patients for systemic immediate-type hypersensitivity reactions to certain drugs including non-steroid...
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Open AccessSingle venom-based immunotherapy effectively protects patients with double positive tests to honey bee and Vespula venom
Referring to individuals with reactivity to honey bee and Vespula venom in diagnostic tests, the umbrella terms “double sensitization” or “double positivity” cover patients with true clinical double allergy and t...
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Open AccessAllergic anaphylaxis due to subcutaneously injected heparin
Heparins are one of the most used class of anticoagulants in daily clinical practice. Despite their widespread application immune-mediated hypersensitivity reactions to heparins are rare. Among these, the dela...
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Article
Open AccessThe concept of "compartment allergy": prilocaine injected into different skin layers
We herein present a patient with delayed-type allergic hypersensitivity against prilocaine leading to spreading eczematous dermatitis after subcutaneous injections for local anesthesia with prilocaine. Priloca...
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Open AccessOccupational allergy due to seafood delivery: Case report
Sensitization to fish or crustaceans requires intensive skin contact and/or airway exposition and therefore especially workers in the seafood processing industry may develop an occupational seafood allergy. Ho...
