3 Result(s)
within
Ashley Wysong
Molecular Medicine
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Article
Cancer cachexia’s metabolic signature in a murine model confirms a distinct entity
Despite recent consensus definitions, lack of specific biomarkers remains a hurdle towards a more accurate and efficient diagnosis of cancer cachexia, distinguishing cachexia as a separate entity from other wa...
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Article
Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia
Cancer cachexia is a severe wasting syndrome characterized by the progressive loss of lean body mass and systemic inflammation. Inhibiting the signaling of the transcription factor nuclear factor kappa B (NF-κ...
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Article
Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations
Cancer cachexia remains a challenging clinical problem with complex pathophysiology and unreliable diagnostic tools. A blood test to detect this metabolic derangement would aid in early treatment of these pati...
