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Challenges in identifying predictors of subsequent keratinocyte carcinoma development: an institutional cohort analysis
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Article
Open AccessIntegrating the 40-Gene Expression Profile (40-GEP) Test Improves Metastatic Risk-Stratification Within Clinically Relevant Subgroups of High-Risk Cutaneous Squamous Cell Carcinoma (cSCC) Patients
The validated 40-gene expression profile (40-GEP) test independently stratifies risk of regional or distant metastasis for cutaneous squamous cell carcinoma (cSCC) tumors with high-risk clinicopathologic featu...
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Article
Analysis of mutations in cutaneous squamous cell carcinoma reveals novel genes and mutations associated with patient-specific characteristics and metastasis: a systematic review
Cutaneous squamous cell carcinoma (SCC) causes approximately 1,000,000 cases and 9000 deaths each year in the United States. While individual tumor sequencing studies have discovered driver mutations in SCC, t...
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Article
PD-1 inhibition therapy for advanced cutaneous squamous cell carcinoma: a retrospective analysis from the University of Southern California
Approximately 5% of patients with cutaneous squamous cell carcinoma (CSCC) may develop recurrent or metastatic disease. The management of such cases is challenging and requires multi-disciplinary care. Immunot...
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Article
What Is New in Occupational Allergic Contact Dermatitis in the Year of the COVID Pandemic?
This article aims to summarize some recent trends in occupational allergic contact dermatitis (ACD), including dermatitis related to pandemic-level personal protective equipment in healthcare workers, hazards ...
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Chapter
Skin Grafts
Skin grafts have become a mainstay of the reconstructive ladder with primary subtypes being full-thickness, split-thickness, composite, and free cartilage skin grafts. Full-thickness skin grafts (FTSGs) contai...
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Basal Cell Carcinoma
Basal cell carcinoma (BCC) is the most common cancer in the United States. BCC is categorized by its clinical appearance and histology. The tumor subtype, anatomical location and patient’s health are factored ...
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Article
Literature Review of Cosmetic Procedures in Men: Approaches and Techniques are Gender Specific
The proportion of men receiving non-surgical cosmetic procedures has risen substantially in recent years. Various physiologic, anatomic, and motivational considerations differentiate the treatments for male an...
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Article
Laser Revision and Rehabilitation of Mohs Micrographic Surgical Scars
The use of Mohs micrographic surgery has become standard of care to treat a multitude of skin cancers to ensure tissue preservation. However, with any skin surgery, a cutaneous scar is the byproduct, and thus,...
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Article
Open AccessLow rate of dermatology outpatient visits in Asian-Americans: an initial survey study for associated patient-related factors
Asian-Americans represent the fastest growing minority group in the United States, but are under-represented patients in outpatient dermatology clinics. At the same time, skin cancer rates in individuals of As...
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Article
Cancer cachexia’s metabolic signature in a murine model confirms a distinct entity
Despite recent consensus definitions, lack of specific biomarkers remains a hurdle towards a more accurate and efficient diagnosis of cancer cachexia, distinguishing cachexia as a separate entity from other wa...
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Article
Metabolic derangements in the gastrocnemius and the effect of Compound A therapy in a murine model of cancer cachexia
Cancer cachexia is a severe wasting syndrome characterized by the progressive loss of lean body mass and systemic inflammation. Inhibiting the signaling of the transcription factor nuclear factor kappa B (NF-κ...
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Metabolomic analysis of cancer cachexia reveals distinct lipid and glucose alterations
Cancer cachexia remains a challenging clinical problem with complex pathophysiology and unreliable diagnostic tools. A blood test to detect this metabolic derangement would aid in early treatment of these pati...