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    Article

    Does Parkinson’s disease start in the gut?

    Parkinson’s disease (PD) is pathologically characterized by the presence of intraneuronal inclusions, termed Lewy bodies and Lewy neurites, whose main component is alpha-synuclein. Based on the topographic dis...

    Arthur Lionnet, Laurène Leclair-Visonneau, Michel Neunlist in Acta Neuropathologica (2018)

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    Open Access

    Characterisation of tau in the human and rodent enteric nervous system under physiological conditions and in tauopathy

    Tau is normally a highly soluble phosphoprotein found predominantly in neurons. Six different isoforms of tau are expressed in the adult human CNS. Under pathological conditions, phosphorylated tau aggregates ...

    Arthur Lionnet, Matthew A. Wade in Acta Neuropathologica Communications (2018)

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    Article

    Enteric alpha-synuclein expression is increased in Crohn’s disease

    Alice Prigent, Arthur Lionnet, Emilie Durieu, Guillaume Chapelet in Acta Neuropathologica (2019)