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Article
Open AccessSARS-CoV-2 vaccination elicits broad and potent antibody effector functions to variants of concern in vulnerable populations
SARS-CoV-2 variants have continuously emerged in the face of effective vaccines. Reduced neutralization against variants raises questions as to whether other antibody functions are similarly compromised, or if...
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Article
Open AccessThree doses of BNT162b2 vaccine confer neutralising antibody capacity against the SARS-CoV-2 Omicron variant
We report the levels of neutralising antibodies against Wuhan, Delta and Omicron variants in unimmunized infected (group 1), immunised and boosted (group 2) and infected immunised and boosted (group 3) adult i...
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Article
Open AccessThe prior infection with SARS-CoV-2 study (PICOV) in nursing home residents and staff - study protocol description and presentation of preliminary findings on symptoms.
The COVID-19 pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has presented itself as one of the most important health concerns of the 2020’s, and hit the geriatric populat...
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Article
Open AccessPredictors of neutralizing antibody response to BNT162b2 vaccination in allogeneic hematopoietic stem cell transplant recipients
Factors affecting response to SARS-CoV-2 mRNA vaccine in allogeneic hematopoietic stem cell transplantation (allo-HCT) recipients remain to be elucidated.
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Article
Immunological mechanisms of vaccine-induced protection against COVID-19 in humans
Most COVID-19 vaccines are designed to elicit immune responses, ideally neutralizing antibodies (NAbs), against the SARS-CoV-2 spike protein. Several vaccines, including mRNA, adenoviral-vectored, protein subu...
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Article
Open AccessAntibody avidity, persistence, and response to antigen recall: comparison of vaccine adjuvants
Differences in innate immune ‘imprinting’ between vaccine adjuvants may mediate dissimilar effects on the quantity/quality of persisting adaptive responses. We compared antibody avidity maturation, antibody/me...
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Protocol
Fc Glycosylation Characterization of Human Immunoglobulins G Using Immunocapture and LC-MS
Immunoglobulins G (IgG) are proteins produced by the immune system of higher life forms that play a central role in the defense against microbial pathogens. IgG bind pat...
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Article
Immunity and immunopathology in early human life
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Article
Breastfeeding-related maternal microchimerism
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Article
Transfer of maternal immunity and programming of the newborn immune system
As placental mammals, the pregnant women and the fetus have intense and prolonged interactions during gestation. There is increasing evidence that multiple molecular as well as cellular components originating ...
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Article
Do PI3-kinase mutations drive T cells insane?
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Article
Open AccessCD4+ T lymphocyte response to primary CMV infection
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Open AccessMother and fetal immunity to cytomegalovirus
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Article
Erratum to: Engagement of TNF mRNA by an endotoxin-inducible cytoplasmic protein
Some of the data in Fig. 1B was reported incorrectly. The correct version is presented below:
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Article
Engagement of Tumor Necrosis Factor mRNA by an Endotoxin-Inducible Cytoplasmic Protein
Tumor necrosis factor (TNF) production by macrophages plays an important role in the host response to infection. TNF-α gene expression in RAW 264.7 macrophages is predominantly regulated at the translational leve...
