4 Result(s)
within
Armen Abnousi
Life Sciences
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Article
Open AccessSnapHiC: a computational pipeline to identify chromatin loops from single-cell Hi-C data
Single-cell Hi-C (scHi-C) analysis has been increasingly used to map chromatin architecture in diverse tissue contexts, but computational tools to define chromatin loops at high resolution from scHi-C data are...
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Protocol
Proximity Ligation-Assisted ChIP-Seq (PLAC-Seq)
Proximity ligation-assisted ChIP-Seq (PLAC-Seq), also known as HiChIP, is a method to detect and quantify chromatin contacts anchored at genomic regions bound by specific proteins or histone modifications. By ...
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Article
An ultra high-throughput method for single-cell joint analysis of open chromatin and transcriptome
Simultaneous profiling of transcriptome and chromatin accessibility within single cells is a powerful approach to dissect gene regulatory programs in complex tissues. However, current tools are limited by mode...
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Article
Open AccessAlignment-free clustering of large data sets of unannotated protein conserved regions using minhashing
Clustering of protein sequences is of key importance in predicting the structure and function of newly sequenced proteins and is also of use for their annotation. With the advent of multiple high-throughput se...
