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Article
Open AccessThe gut microbiome of exudivorous marmosets in the wild and captivity
Mammalian captive dietary specialists like folivores are prone to gastrointestinal distress and primate dietary specialists suffer the greatest gut microbiome diversity losses in captivity compared to the wild...
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Article
Open AccessGeographically dispersed zoonotic tuberculosis in pre-contact South American human populations
Previous ancient DNA research has shown that Mycobacterium pinnipedii, which today causes tuberculosis (TB) primarily in pinnipeds, infected human populations living in the coastal areas of Peru prior to European...
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Article
Open AccessGenomic skimming and nanopore sequencing uncover cryptic hybridization in one of world’s most threatened primates
The Brazilian buffy-tufted-ear marmoset (Callithrix aurita), one of the world’s most endangered primates, is threatened by anthropogenic hybridization with exotic, invasive marmoset species. As there are few gene...
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Article
Dire wolves were the last of an ancient New World canid lineage
Dire wolves are considered to be one of the most common and widespread large carnivores in Pleistocene America1, yet relatively little is known about their evolution or extinction. Here, to reconstruct the evolut...
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Article
Open AccessDifferential DNA methylation of vocal and facial anatomy genes in modern humans
Changes in potential regulatory elements are thought to be key drivers of phenotypic divergence. However, identifying changes to regulatory elements that underlie human-specific traits has proven very challeng...
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Article
Open AccessMetagenomic analysis of dental calculus in ancient Egyptian baboons
Dental calculus, or mineralized plaque, represents a record of ancient biomolecules and food residues. Recently, ancient metagenomics made it possible to unlock the wealth of microbial and dietary information ...
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Article
Open AccessOral microbiome diversity in chimpanzees from Gombe National Park
Historic calcified dental plaque (dental calculus) can provide a unique perspective into the health status of past human populations but currently no studies have focused on the oral microbial ecosystem of oth...
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Article
Open AccessDifferential preservation of endogenous human and microbial DNA in dental calculus and dentin
Dental calculus (calcified dental plaque) is prevalent in archaeological skeletal collections and is a rich source of oral microbiome and host-derived ancient biomolecules. Recently, it has been proposed that ...
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Article
Pre-Columbian mycobacterial genomes reveal seals as a source of New World human tuberculosis
Three 1,000-year-old mycobacterial genomes from Peruvian human skeletons reveal that a member of the Mycobacterium tuberculosis complex derived from seals caused human disease before contact in the Americas.
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Article
Independent evolution of bitter-taste sensitivity in humans and chimpanzees
The ability to sense bitter taste is vital for detecting toxins in food. Phenylthiocarbamide (PTC) is unusual in that to us it tastes either very bitter, or almost tasteless, depending on an individual's genet...