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Chapter
Biologically Relevant Laminins in Regenerative Medicine
Need for biologically relevant . Recent advances in -based allow to expand human in almost unlimited amounts. However, expanded become devoid of natural niche cues and, therefore, may become prone to risk...
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Article
Open AccessClonal culturing of human embryonic stem cells on laminin-521/E-cadherin matrix in defined and xeno-free environment
Lack of robust methods for establishment and expansion of pluripotent human embryonic stem (hES) cells still hampers development of cell therapy. Laminins (LN) are a family of highly cell-type specific basemen...
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Article
Long-term self-renewal of human pluripotent stem cells on human recombinant laminin-511
The development of fully defined culture conditions for human embryonic stem cells (hESCs) should enhance experimental reproducibility, reduce unwanted contaminants and facilitate scale-up production. Rodin et al
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Article
Distinct roles of integrins α6 and α4 in fetal liver hematopoietic stem and progenitor cell homing